Hong Jinsu, Lee Geon Il, Jang Jae-Cheol, Kim Yoo Yong
Department of Agricultural Biotechnology, Center for Food and Bioconvergence, and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, Korea.
Department of Animal Science, University of Minnesota, Saint Paul, MN, USA.
Anim Biosci. 2025 Aug;38(8):1708-1718. doi: 10.5713/ab.24.0796. Epub 2025 Feb 27.
The present study aimed to evaluate the effects of bacteriophage cocktail supplementation in diet of gestation sows on both the sows and their progeny.
A total of 57 F1 multiparous sows (Yorkshire×Landrace) were allotted to one of three treatment groups in a completely randomized design. The sows were fed cornsoybean meal-based diet supplemented with 0%, 0.05%, or 0.10% of a bacteriophage cocktail during the gestation, followed by a common diet during lactation. Body weight and backfat thickness were measured during the trial along with blood collection for immunoglobulin analysis. Fecal samples were collected on 4, 6, 8, and 10 weeks of gestation period to examine fecal microflora. Litter performance and milk composition were investigated at 24 hrs postpartum and on d 21 of lactation.
Increasing bacteriophage cocktail supplementation levels in gestation diets resulted in linear increas (p<0.05) in feed intake of lactating sows and in the weight of live litters, while showing quadratic increas (p<0.05) in litter weight gain from d 0 to 21 of lactation. Dietary treatment had no impact on the serum concentrations of IgG and IgM in the sows. Increasing dietary bacteriophage cocktail levels in gestation diets resulted in a linear increas (p<0.05) in the fat content of colostrum. The elevation of dietary bacteriophage cocktail in microflora of sows resluted in a significant increase (p<0.05) in Lactobacillus count for d 63 and 105 of the gestation period, while concurrently decreasing Escherichia coli (E. coli; p<0.05) and Salmonella (p<0.10) counts during the late gestation period.
The supplementation of a 0.05% bacteriophage cocktail in the diet of gestating sows could improve total litter weight, alive litter weight at birth, and litter weight gain during the lactation. This effect is attributed to positive changes in fecal microflora with an increase of Lactobacillus and a decrease of E. coli and Salmonella.
本研究旨在评估妊娠母猪日粮中添加噬菌体鸡尾酒对母猪及其后代的影响。
采用完全随机设计，将57头F1经产母猪（约克夏×长白）分为三个处理组之一。母猪在妊娠期饲喂以玉米豆粕为基础的日粮，分别添加0%、0.05%或0.10%的噬菌体鸡尾酒，哺乳期饲喂普通日粮。试验期间测量体重和背膘厚度，并采集血液进行免疫球蛋白分析。在妊娠期第4、6、8和10周采集粪便样本，检查粪便微生物群。在产后24小时和哺乳期第21天调查窝产性能和乳汁成分。
妊娠期日粮中噬菌体鸡尾酒添加水平的增加导致泌乳期母猪采食量和活仔窝重呈线性增加（p<0.05），而从泌乳期第0天到第21天窝仔体重增加呈二次增加（p<0.05）。日粮处理对母猪血清IgG和IgM浓度没有影响。妊娠期日粮中噬菌体鸡尾酒水平的增加导致初乳脂肪含量呈线性增加（p<0.05）。日粮中噬菌体鸡尾酒水平的提高导致妊娠期第63天和第105天母猪粪便微生物群中乳酸杆菌数量显著增加（p<0.05），而在妊娠后期同时降低大肠杆菌（p<0.05）和沙门氏菌（p<0.10）数量。
在妊娠母猪日粮中添加0.05%的噬菌体鸡尾酒可以提高总窝重、出生时活仔窝重和哺乳期窝仔体重增加。这种效果归因于粪便微生物群的积极变化，乳酸杆菌增加，大肠杆菌和沙门氏菌减少。
