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无任何确诊呼吸系统疾病的吸烟人群肌肉力量和功能能力评估:一项横断面研究。

Assessment of Muscular Strength and Functional Capacity in Smoker Population Without Any Diagnosed Respiratory Disease: A Cross-Sectional Study.

作者信息

Thibon Christophe, Caty Gilles, Gohy Sophie, Aboubakar Nana Frank, Reychler Gregory

机构信息

Secteur de Kinésithérapie et Ergothérapie, Cliniques Universitaires Saint-Luc (UCL), Avenue Hippocrate 10, 1200 Brussels, Belgium.

Institut de Recherche Expérimentale et Clinique (IREC), Pôle de Pneumologie, ORL & Dermatologie, Université Catholique de Louvain, 1200 Brussels, Belgium.

出版信息

Healthcare (Basel). 2025 Feb 24;13(5):493. doi: 10.3390/healthcare13050493.

DOI:10.3390/healthcare13050493
PMID:40077055
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11899466/
Abstract

: Smoking is a risk factor for chronic obstructive pulmonary disease (COPD) and lung cancer. In addition to pulmonary damages, peripheral muscle impairments are present in this population. Pulmonary limitation is observed in smokers before disease diagnosis, but functional capacity limitations are uncertain, contrary to patients who have already been diagnosed. The aim of this study was to compare muscular strength and endurance between non-smoker and smoker populations without any diagnosed respiratory disease. : This cross-sectional study assessed subjects without diagnosed respiratory disease in terms of physical capacity using two tests (one-minute sit-to-stand test (STST) and Jamar dynamometer test (JDT)). : The sample consisted of 147 subjects. The number of repetitions and the muscle strength were lower in the smoker than in the non-smoker population (28.5 ± 8.7 vs. 33.5 ± 8.2 ( < 0.001), and 38.2 ± 10.1 vs. 42.4 ± 10.5 ( = 0.04), respectively). The relative change in heart rate during STST was lower in the smokers compared to the non-smokers ( = 0.01). No significant differences were found based on gender. : Smokers without alcohol or drug dependence and without diagnosed lung disease exhibit non-clinically but statistically reduced muscular strength and endurance. Their heart rate response to exercise is also reduced.

摘要

吸烟是慢性阻塞性肺疾病(COPD)和肺癌的危险因素。除了肺部损伤外,该人群还存在外周肌肉功能障碍。在疾病诊断前,吸烟者就出现了肺功能受限,但与已确诊患者不同,其功能能力受限情况尚不确定。本研究的目的是比较无任何已确诊呼吸系统疾病的非吸烟人群和吸烟人群之间的肌肉力量和耐力。:这项横断面研究使用两项测试(一分钟坐立试验(STST)和握力计试验(JDT)),从身体能力方面评估了未确诊呼吸系统疾病的受试者。:样本包括147名受试者。吸烟者的重复次数和肌肉力量低于非吸烟人群(分别为28.5±8.7对33.5±8.2(<0.001),以及38.2±10.1对42.4±10.5(=0.04))。与非吸烟者相比,吸烟者在STST期间心率的相对变化更低(=0.01)。基于性别未发现显著差异。:无酒精或药物依赖且无已确诊肺部疾病的吸烟者表现出非临床但统计学上降低的肌肉力量和耐力。他们对运动的心率反应也降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acb1/11899466/fbe4a6ad8134/healthcare-13-00493-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acb1/11899466/fbe4a6ad8134/healthcare-13-00493-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acb1/11899466/fbe4a6ad8134/healthcare-13-00493-g001a.jpg

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Impaired Skeletal Muscle in Patients with Stable Chronic Obstructive Pulmonary Disease (COPD) Compared with Non-COPD Patients.稳定期慢性阻塞性肺疾病(COPD)患者的骨骼肌功能受损与非 COPD 患者相比。
Int J Chron Obstruct Pulmon Dis. 2023 Jul 19;18:1525-1532. doi: 10.2147/COPD.S396728. eCollection 2023.
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Tobacco smoking and vascular biology and function: evidence from human studies.
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Pflugers Arch. 2023 Jul;475(7):797-805. doi: 10.1007/s00424-023-02805-z. Epub 2023 Mar 24.
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