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Determination of 4-amino-3-(p-chlorophenyl)butyric acid (baclofen) in plasma by high-performance liquid chromatography.

作者信息

Harrison P M, Tonkin A M, McLean A J

出版信息

J Chromatogr. 1985 May 3;339(2):424-8. doi: 10.1016/s0378-4347(00)84675-7.

DOI:10.1016/s0378-4347(00)84675-7
PMID:4008583
Abstract
摘要

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1
Determination of 4-amino-3-(p-chlorophenyl)butyric acid (baclofen) in plasma by high-performance liquid chromatography.高效液相色谱法测定血浆中4-氨基-3-(对氯苯基)丁酸(巴氯芬)
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[Identification and quantitative determination of baclofen in human blood by HPLC with mass spectrometry detection].
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High-performance liquid chromatographic analysis of baclofen in plasma and urine of man after precolumn extraction and derivatization with o-phthaldialdehyde.人血浆和尿液中巴氯芬经柱前萃取并用邻苯二甲醛衍生化后的高效液相色谱分析
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Toxicological analysis of a fatal baclofen (Lioresal) ingestion.一例致命性巴氯芬(力奥来素)摄入的毒理学分析。
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Resolution of the stereoisomers of baclofen by high performance liquid chromatography.通过高效液相色谱法拆分巴氯芬的立体异构体。
J Neurosci Methods. 1984 Jan;10(1):23-8. doi: 10.1016/0165-0270(84)90076-1.

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Validated Method for the Quantification of Baclofen in Human Plasma Using Solid-Phase Extraction and Liquid Chromatography-Tandem Mass Spectrometry.采用固相萃取和液相色谱-串联质谱法测定人血浆中巴氯芬的验证方法
J Anal Toxicol. 2016 Mar;40(2):117-23. doi: 10.1093/jat/bkv125. Epub 2015 Nov 4.
2
Management of severe spasticity with intrathecal baclofen delivered by a manually operated pump.使用手动泵鞘内注射巴氯芬治疗严重痉挛
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Suitability of various noninfinity area under the plasma concentration-time curve (AUC) estimates for use in bioequivalence determinations: relationship to AUC from zero to time infinity (AUC0-INF).
各种血浆浓度-时间曲线下非无穷大面积(AUC)估计值在生物等效性测定中的适用性:与从零到时间无穷大的AUC(AUC0-INF)的关系。
Pharm Res. 1991 Apr;8(4):512-7. doi: 10.1023/a:1015863530888.