Paschen V K, Andreae W, Strobel B, Gabl F, Mokricky C, Flückiger J W, Hänseler E, Schlebusch H, Schneider C, Poppe W A
J Clin Chem Clin Biochem. 1985 Apr;23(4):187-96.
The ISE 2020 electrolyte analyzer has been investigated within the framework of a multicentre evaluation in 5 laboratories. The users quickly learnt how to operate the instrument, and changes of personnel in the course of the trial had no influence upon the quality of the results. Regardless of the sample material (blood, serum, plasma) and the manner of introduction of the sample (manual or with the sampler), the in-series precision averaged 0.8% for sodium and 1.0% for potassium. The day-to-day precision was only slightly worse, at 1% (Na) and 2% (K). The recover, referred to the nominal values of control sera, averaged 100.3%. Investigations of linearity for potassium in the range from 0 to 12 mmol/l and for sodium in the range from 80 to 180 mmol/l confirmed a linear course of the measurements in the range of electrolyte concentrations of diagnostic interest. In extensive investigations by the testers with serum and plasma samples, the results showed good comparability with those from flame emission photometry. The mean values obtained by the two methods differed from one another only minimally in the case of sodium and potassium. The results with whole blood and with plasma prepared from it were in very close agreement. The ISE 2020 is regarded as highly suitable for routine work and emergency investigations in the central laboratory as well as for wards and operating rooms.
ISE 2020电解质分析仪已在5个实验室进行的多中心评估框架内进行了研究。用户很快就学会了如何操作该仪器，并且在试验过程中人员变动对结果质量没有影响。无论样品材料（血液、血清、血浆）以及样品引入方式（手动或使用采样器）如何，钠的系列内精密度平均为0.8%，钾为1.0%。日间精密度略差，钠为1%，钾为2%。相对于对照血清的标称值，回收率平均为100.3%。对钾在0至12 mmol/l范围内以及钠在80至180 mmol/l范围内的线性研究证实，在具有诊断意义的电解质浓度范围内测量呈线性过程。测试人员对血清和血浆样本进行的广泛研究表明，结果与火焰发射光度法的结果具有良好的可比性。两种方法获得的钠和钾的平均值彼此仅略有差异。全血及其制备的血浆的结果非常一致。ISE 2020被认为非常适合中心实验室以及病房和手术室的常规工作和急诊检查。
