Zhang Xiaoling, Wu Jinhui
Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China.
Blood Press. 2025 Dec;34(1):2468172. doi: 10.1080/08037051.2025.2468172. Epub 2025 Mar 17.
This study examined temporal trends in hypertension prevalence across China (2002-2019), analyzing age-, sex-, and region-specific disparities and identifying key risk factors.
A retrospective analysis was conducted using data from the China Chronic Disease and Risk Factor Surveillance (CCDRFS) program, involving 120,000 adults aged ≥18 years. Descriptive statistics were used to calculate prevalence rates, and multivariable logistic regression analyzed associations with age, sex, BMI, smoking, alcohol consumption, and physical inactivity.
Hypertension prevalence increased significantly from 18.9% (2002) to 29.6% (2019) (P<0.001). The sharpest rise occurred among adults aged 18-44 years, tripling from 5.3% to 12.8%. By 2019, prevalence was higher in men (34.2%) than women (25.4%), with the western regions showing the highest rates (32.9%). Key risk factors included aging (OR=1.72), elevated BMI (OR=1.85), smoking (OR=1.32), alcohol use (OR=1.28), and physical inactivity (OR=1.18) (P<0.05 for all).
Hypertension prevalence in China has surged over two decades, disproportionately affecting younger adults and men. Regional disparities and modifiable lifestyle factors underscore the urgency for tailored prevention strategies targeting high-risk populations. Future research should explore mechanisms driving these trends and optimize integrated interventions to curb this public health burden.
本研究调查了中国2002 - 2019年期间高血压患病率的时间趋势,分析了年龄、性别和地区特异性差异,并确定了关键风险因素。
使用中国慢性病与危险因素监测(CCDRFS)项目的数据进行回顾性分析,该项目涉及120,000名年龄≥18岁的成年人。采用描述性统计计算患病率,多变量逻辑回归分析与年龄、性别、体重指数、吸烟、饮酒和身体活动不足的关联。
高血压患病率从2002年的18.9%显著上升至2019年的29.6%(P<0.001)。18 - 44岁成年人的患病率上升最为显著,从5.3%增至12.8%,增长了两倍。到2019年,男性患病率(34.2%)高于女性(25.4%),西部地区患病率最高(32.9%)。关键风险因素包括老龄化(比值比[OR]=1.72)、体重指数升高(OR=1.85)、吸烟(OR=1.32)、饮酒(OR=1.28)和身体活动不足(OR=1.18)(所有P<0.05)。
中国高血压患病率在二十多年间急剧上升,对年轻成年人和男性的影响尤为严重。地区差异和可改变的生活方式因素凸显了针对高危人群制定个性化预防策略的紧迫性。未来的研究应探索推动这些趋势的机制,并优化综合干预措施以减轻这一公共卫生负担。