Zhang Jiarui, Shan Yubo, Zhang Yingzhen, Ye Xingchen, Song Yuejia, Sun Changfu, Pang Pai
Department of Oromaxillofacial-Head and Neck Surgery, School and Hospital of Stomatology, Liaoning Provincial Key Laboratory of Oral Diseases, China Medical University, Shenyang, 110002, China.
Sci Rep. 2025 Mar 17;15(1):9072. doi: 10.1038/s41598-025-93535-y.
The aim was to analyze the factors influencing the psychological status and cognitive function in postoperative head and neck tumor (HNT) patients. 170 patients, including 90 benign HNT (BHNT) patients and 80 malignant HNT (MHNT) patients, were included in this study. Psychological status was evaluated using the distress thermometer. Cognitive function was evaluated using the Multiple Ability Self-Reported Questionnaire. The psychological status and cognitive function were both statistically significantly better in BHNT patients than in MHNT patients (P < 0.001 and P < 0.001, respectively). MHNT patients in the moderate and severe appearance defect groups had a higher incidence of psychological distress than those in the no facial appearance defect group (P = 0.006 and P = 0.011, respectively). Both BHNT and MHNT patients in the group under the age of 60 had a higher incidence of psychological distress than those in the group over the age of 60 (P = 0.017 and P = 0.017, respectively). Educational level of both BHNT and MHNT patients was negatively correlated with the extent of cognitive impairment (P = 0.012 and P = 0.004, respectively). The influence of postoperative time on the psychological condition varied in different groups. Postoperative time of both BHNT and MHNT patients was negatively correlated with the extent of cognitive impairment (P = 0.027 and P < 0.001, respectively).
目的是分析影响头颈肿瘤（HNT）术后患者心理状态和认知功能的因素。本研究纳入了170例患者，包括90例良性HNT（BHNT）患者和80例恶性HNT（MHNT）患者。使用苦恼温度计评估心理状态。使用多项能力自陈问卷评估认知功能。BHNT患者的心理状态和认知功能在统计学上均显著优于MHNT患者（分别为P < 0.001和P < 0.001）。中度和重度外观缺陷组的MHNT患者心理困扰发生率高于无面部外观缺陷组（分别为P = 0.006和P = 0.011）。60岁以下组的BHNT和MHNT患者心理困扰发生率均高于60岁以上组（分别为P = 0.017和P = 0.017）。BHNT和MHNT患者的教育水平均与认知障碍程度呈负相关（分别为P = 0.012和P = 0.004）。术后时间对心理状况的影响在不同组中有所不同。BHNT和MHNT患者的术后时间均与认知障碍程度呈负相关（分别为P = 0.027和P < 0.001）。
