两种“抗攻击”化合物（一种茚并吡啶和一种苯并硫氮杂䓬）对大鼠休克诱导的防御性打斗行为的影响。
The effects of two "anti-aggressive" compounds, an indenopyridine and a benzothiazepin, on shock-induced defensive fighting in rats.
作者信息
Bell R, Brown K
机构信息
Department of Psychology Queen's University, Belfast, Ireland.
出版信息
Prog Neuropsychopharmacol. 1979;3(4):399-402. doi: 10.1016/0364-7722(79)90053-5.
PMID:400995
Abstract
- An indenopyridine (YG19-256) and a benzothiazepin (thiazesim) were investigated in rats for possible effects on shock-induced defensive fighting, shock reactivity and locomotor activity. 2. YG19-256 significantly reduced aggression at the higher dose levels employed. Thiazesim produced no significant decrease in aggression at the dose levels used. 3. Neither compound produced any consistent effect on shock reactivity or locomotor activity.
摘要
- 研究了一种茚并吡啶（YG19 - 256）和一种苯并硫氮䓬（噻西泮）对大鼠休克诱导的防御性争斗、休克反应性和运动活动的可能影响。2. YG19 - 256在所用的较高剂量水平下显著降低了攻击性。噻西泮在所用剂量水平下未使攻击性显著降低。3. 两种化合物对休克反应性或运动活动均未产生任何一致的影响。
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