Cheng Zhaojun, Gong Yan, Gan Yanchi, He Jiahui, Liang De, Ren Hui, Jiang Xiaobing
Minimally Invasive Spinal Surgery, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou Guangdong, 510405, P. R. China.
Postdoctoral Research Station of Guangzhou University of Chinese Medicine, Guangzhou Guangdong, 510405, P. R. China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2025 Mar 15;39(3):341-345. doi: 10.7507/1002-1892.202409010.
To investigate correlation between preoperative C slope (C2S) and effectiveness at 2 years after short-segment anterior cervical discectomy and fusion (ACDF), with the aim of providing reliable indicators for predicting effectiveness.
One hundred and eighteen patients with cervical spondylotic myelopathy, who received short-segment ACDF between January 2018 and December 2022 and met the selection criteria, were enrolled in the study. There were 46 males and 72 females, aged from 26 to 80 years, with a mean age of 53.6 years. The operative duration was (127.6±33.46) minutes and the intraoperative blood loss was (34.75±30.40) mL. All patients were followed up 2 years. The pre- and post-operative Neck Disability Index (NDI), Japanese Orthopaedic Association (JOA) score, and visual analogue scale (VAS) score for pain were recorded. Based on the anteroposterior and lateral cervical X-ray films, the sagittal parameters of the cervical spine were measured [C -C Cobb angle, C -C Cobb angle, T slope, C2S, sagittal segmental angle (SSA) of the surgical segment, and average surgical disc height (ASDH) of the surgical segment]. Statistical analyses were performed to assess the differences in these indicators between pre- and post-operation, as well as the correlations between the preoperative C2S and the JOA score, NDI, and VAS score at 2 years after operation. The patients were allocated into group A (C2S >11.73°) and group B (C2S≤ 11.73°) according to the median value of the preoperative C2S (11.73°). The JOA score, NDI, and VAS score before operation and at 2 years after operation, as well as the differences between pre- and post-operative values (change values), were compared between the two groups.
The T slope, C -C Cobb angle, C -C Cobb angle, SSA, and ASDH at immediate after operation and JOA score, NDI, and VAS score at 2 years after operation significantly improved in 118 patients when compared with preoperative ones ( <0.05). Pearson correlation analysis showed that preoperative C2S was not correlated with JOA score and NDI at 2 years after operation ( >0.05), but negatively correlated with VAS score ( <0.05). There were 59 patients with preoperative C2S>11.73° (group A) and 59 with C2S≤11.73° (group B). There was no significant difference in preoperative JOA score, NDI, and VAS score between the two groups ( >0.05). There were significant differences in VAS score at 2 year after operation and the change value between the two groups ( <0.05); there was no significant difference in the JOA score and NDI ( >0.05).
Patients with cervical spondylotic myelopathy and a higher preoperative C2S exhibited superior long-term pain relief and effectiveness following short-segment ACDF.
探讨术前C斜率(C2S)与短节段颈椎前路椎间盘切除融合术(ACDF)术后2年疗效之间的相关性,旨在为预测疗效提供可靠指标。
选取2018年1月至2022年12月期间接受短节段ACDF且符合入选标准的118例脊髓型颈椎病患者纳入研究。其中男性46例,女性72例,年龄26~80岁,平均年龄53.6岁。手术时间为(127.6±33.46)分钟,术中出血量为(34.75±30.40)毫升。所有患者均随访2年。记录术前及术后的颈部功能障碍指数(NDI)、日本骨科协会(JOA)评分及视觉模拟评分法(VAS)疼痛评分。根据颈椎正侧位X线片测量颈椎矢状位参数[C2-C7 Cobb角、C3-C7 Cobb角、T1斜率、C2S、手术节段矢状节段角(SSA)及手术节段平均手术椎间盘高度(ASDH)]。进行统计学分析以评估这些指标术前与术后的差异,以及术前C2S与术后2年JOA评分、NDI及VAS评分之间的相关性。根据术前C2S的中位数(11.73°)将患者分为A组(C2S>11.73°)和B组(C2S≤11.73°)。比较两组术前及术后2年的JOA评分、NDI及VAS评分,以及术前与术后值的差异(变化值)。
118例患者术后即刻的T1斜率、C2-C7 Cobb角、C3-C7 Cobb角、SSA及ASDH,以及术后2年的JOA评分、NDI及VAS评分与术前相比均有显著改善(P<0.05)。Pearson相关性分析显示,术前C2S与术后2年的JOA评分及NDI无相关性(P>0.05),但与VAS评分呈负相关(P<0.05)。术前C2S>11.73°的患者59例(A组),C2S≤11.73°的患者59例(B组)。两组术前JOA评分、NDI及VAS评分差异无统计学意义(P>0.05)。两组术后2年VAS评分及变化值差异有统计学意义(P<0.05);JOA评分及NDI差异无统计学意义(P>0.05)。
脊髓型颈椎病患者术前C2S较高者,短节段ACDF术后长期疼痛缓解及疗效更佳。