Zhang Hui, Wang Kai, Huang Shuai, Cui Ziheng, Chen Biqiang
College of Life Science and Technology Beijing University of Chemical Technology Beijing P.R. China.
Eng Life Sci. 2025 Mar 17;25(3):e70016. doi: 10.1002/elsc.70016. eCollection 2025 Mar.
Deep eutectic solvents (DESs) hold the potential to serve as a sustainable and environmentally friendly substitute for supercritical fluids, ionic liquids, and organic solvents. Moreover, DESs have been demonstrated to assist in stabilizing the structure of enzyme. The enzymatic synthesis of epoxy vegetable oil in a DES-system was developed in this study, and the influence of DESs viscosity on the epoxidation system was investigated for the first time. The results demonstrated that the epoxy value reached 8.97, and the double bond conversion rate was 82.48%. The viscosity of the reaction system decreased from 209.32 to 91.35 (mPa·s). The application of DES in epoxidation was confirmed through structural characterization, indicating that eutectic solvents could serve as substitutes for toxic and volatile organic solvents in synthesizing high-epoxide vegetable oils using an enzymatic method, thus facilitating the production of environmentally friendly plasticizers.
深共熔溶剂（DESs）有望成为超临界流体、离子液体和有机溶剂的可持续且环境友好的替代品。此外，已证明DESs有助于稳定酶的结构。本研究开发了在DES体系中酶法合成环氧植物油的方法，并首次研究了DESs粘度对环氧化体系的影响。结果表明，环氧值达到8.97，双键转化率为82.48%。反应体系的粘度从209.32降至91.35（mPa·s）。通过结构表征证实了DES在环氧化中的应用，表明共熔溶剂可作为有毒挥发性有机溶剂的替代品，用于酶法合成高环氧值植物油，从而有利于生产环境友好型增塑剂。
