深入探究肺淋巴管。
An in-depth look at lung lymphatics.
作者信息
Jackson David G
机构信息
University of Oxford, MRC Translational Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine , Oxford, UK.
出版信息
J Exp Med. 2025 May 5;222(5). doi: 10.1084/jem.20250119. Epub 2025 Mar 19.
Abstract
In this issue of JEM, Cleary et al. (https://doi.org/10.1084/jem.20241359) present a new intravital imaging technique using a 3D-printed window device that enables lung lymphatics and their participation in immune cell trafficking events to be visualized in action for the first time in mechanically ventilated mice.
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本文引用的文献
1
The Lymphatic Vasculature in Lung Homeostasis and Disease.肺稳态与疾病中的淋巴管系统
Annu Rev Physiol. 2025 Feb;87(1):421-446. doi: 10.1146/annurev-physiol-022724-105311. Epub 2025 Feb 3.
2
Buttons and Zippers: Endothelial Junctions in Lymphatic Vessels.纽扣与拉链：淋巴管中的内皮连接
Cold Spring Harb Perspect Med. 2022 Dec 1;12(12):a041178. doi: 10.1101/cshperspect.a041178.
3
Imaging leukocyte migration through afferent lymphatics.通过输入淋巴管成像白细胞迁移。
Immunol Rev. 2022 Mar;306(1):43-57. doi: 10.1111/imr.13030. Epub 2021 Oct 27.
4
Adventitial Cuffs: Regional Hubs for Tissue Immunity.血管外膜袖套：组织免疫的区域枢纽。
Trends Immunol. 2019 Oct;40(10):877-887. doi: 10.1016/j.it.2019.08.002. Epub 2019 Sep 13.
5
Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction.表达外周组织抗原的淋巴管内皮细胞在CD4 T细胞耐受性诱导中的作用。
Nat Commun. 2015 Apr 10;6:6771. doi: 10.1038/ncomms7771.
6
Stabilized imaging of immune surveillance in the mouse lung.稳定成像监测小鼠肺部的免疫监视。
Nat Methods. 2011 Jan;8(1):91-6. doi: 10.1038/nmeth.1543. Epub 2010 Dec 12.
7
Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels.预制门有利于树突状细胞进入输入淋巴管。
J Exp Med. 2009 Dec 21;206(13):2925-35. doi: 10.1084/jem.20091739. Epub 2009 Dec 7.
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