Mustafa Muna B, Hamoudi Walid K, Khashan Khawla S
Department of Applied Sciences, University of Technology, Baghdad, Iraq.
Electrical Engineering Technical College, Middle Technical University, Baghdad, Iraq.
Lasers Med Sci. 2025 Mar 19;40(1):149. doi: 10.1007/s10103-025-04405-y.
Because it is difficult to totally remove ink particles trapped in the skin, tattoo removal-especially for deeply and densely pigmented types-remains a substantial issue. This frequently leads to scarring, persistent pigmentation, or an incomplete removal. Significant promise in resolving this problem since high-peak power pulsed Nd: YAG lasers can efficiently target ink particles even in deeper skin layers, they have shown. The purpose of this study is to assess how well the Nd: YAG laser uses tissue photodisruption to remove deeply embedded tattoo ink. High intensity Nd: YAG lasers provide a very efficient way to remove tattoos by dissolving ink particles with the least amount of harm to surrounding tissue. Two sessions of Q-switched Nd: YAG (1064 nm) laser treatment was performed on a 36-year-old woman who had a very deep black tattoo on her arm. When the tattooed area was treated with a laser beam with a 6-mm spot size and 5 J/cm² fluence. After two months, the process was repeated, and the last evaluation was carried out one month after the second therapy. For histologic research objectives, one local white rabbit was also included in this investigation. Under general anesthesia, the rabbit was injected with tattoos of black pigment and given a single session. Black ink significantly lightened without leaving any scars and a crust formed right after. The spectroscopic properties of black tattoo ink were examined. Following laser exposure, there was a noticeable decrease in the appearance of the ink without any indication of inflammation or cell growth. Within ten days, the skin's texture improved and the tattoo was 85% cleared after two laser sessions without blistering or changes in texture. Black ink granules were efficiently broken down by laser-induced cavitation, creating structures resembling bubbles. Ink fragments were phagocytized and distributed throughout the layers of the skin, whereas histological examination of treated black tattooed rabbit skin revealed a notable decrease in ink particle size without inflammatory reactions. albeit there was no injury to the epidermis, the 1064 nm Nd: YAG laser produced deep vacuoles and selective absorption by black ink, albeit localized inflammatory reactions were noted. The 1064 nm Q-switched Nd: YAG laser, operating at 6ns, demonstrated safety and effectiveness for deep tattoo removal. It achieved 85% clearance after two sessions, without inducing pigmentation changes.
由于很难完全清除困在皮肤中的墨水颗粒,纹身去除——尤其是对于颜色深且浓的纹身类型——仍然是一个重大问题。这经常会导致疤痕、色素沉着持续存在或去除不完全。自高峰值功率脉冲Nd:YAG激光已表明即使在更深的皮肤层也能有效靶向墨水颗粒以来,在解决这个问题上有了重大进展。本研究的目的是评估Nd:YAG激光利用组织光破碎来去除深层嵌入的纹身墨水的效果如何。高强度Nd:YAG激光提供了一种非常有效的去除纹身的方法,即通过溶解墨水颗粒,同时对周围组织造成最小的伤害。对一名36岁手臂上有非常深的黑色纹身的女性进行了两次调Q Nd:YAG(1064nm)激光治疗。当用光斑尺寸为6mm、能量密度为5J/cm²的激光束治疗纹身区域时。两个月后,重复该过程,最后一次评估在第二次治疗后一个月进行。为了进行组织学研究,本研究还纳入了一只本地白兔。在全身麻醉下,给兔子注射黑色颜料纹身并进行单次治疗。黑色墨水明显变浅,没有留下任何疤痕,之后立即形成痂皮。对黑色纹身墨水的光谱特性进行了检查。激光照射后,墨水的外观明显减少,没有任何炎症或细胞生长的迹象。在十天内,皮肤质地得到改善,经过两次激光治疗后纹身清除了85%,没有出现水泡或质地变化。激光诱导的空化有效地分解了黑色墨水颗粒,形成了类似气泡的结构。墨水碎片被吞噬并分布在皮肤各层,而对经治疗的黑色纹身兔皮肤的组织学检查显示墨水颗粒大小显著减小,没有炎症反应。尽管对表皮没有损伤,但1064nm Nd:YAG激光产生了深部空泡并被黑色墨水选择性吸收,尽管注意到有局部炎症反应。运行在6ns的1064nm调Q Nd:YAG激光在去除深部纹身方面显示出安全性和有效性。两次治疗后实现了85%的清除率,且未引起色素沉着变化。