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用于LED口腔护理设备中有效光疗的光学分析。

Optical analysis for effective phototherapy in an LED oral care device.

作者信息

Shin Younghoon, Song Woosub, Shin In Hee, Ji Dae Won, Min Kyoung Jae, Ahn Sun-Hee

机构信息

Bio & Health Photonics Research Center, Korea Photonics Technology Institute (KOPTI), Gwangju 61007, Republic of Korea.

Osstem Implant Unit Chair R&D Center, Osstem Implant Co., LTD, Seoul 07789, Republic of Korea.

出版信息

Biomed Opt Express. 2025 Feb 6;16(3):922-934. doi: 10.1364/BOE.553671. eCollection 2025 Mar 1.

DOI:10.1364/BOE.553671
PMID:40109532
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11919360/
Abstract

This paper investigates the advanced capabilities of light-emitting diodes (LEDs) in oral care devices, emphasizing their versatility in wavelength control and ability to reach complex areas within the oral cavity. While LEDs enable precise dosage control and adjustable penetration depths, existing oral care devices are often limited to single-wavelength designs, primarily targeting anterior teeth whitening or lateral surfaces, thereby failing to provide comprehensive oral coverage. To address these limitations, this study introduces a novel LED-based oral care device integrating three distinct wavelengths: blue for antibacterial effects, green for anti-inflammatory effects, and red for preventive and therapeutic applications. Using computed tomography (CT) data, upper and lower dental arch trajectories were acquired to design a flexible printed circuit board (FPCB) that conforms to the natural curvature of the dental arch. Strategically placed LEDs on the FPCB ensure uniform light distribution and optimized irradiance across the entire oral cavity. This research systematically determines the optimal design parameters and operating conditions necessary for achieving appropriate irradiance density, including LED placement, operating time, and power control through driving current and duty cycles. The findings demonstrate a practical and effective approach to overcoming the current limitations of LED oral care devices, significantly enhancing their performance and applicability in dental phototherapy.

摘要

本文研究了发光二极管(LED)在口腔护理设备中的先进功能,强调了其在波长控制方面的多功能性以及照亮口腔内复杂区域的能力。虽然LED能够实现精确的剂量控制和可调节的穿透深度,但现有的口腔护理设备通常局限于单波长设计,主要针对前牙美白或侧面,因此无法提供全面的口腔覆盖。为了解决这些限制,本研究引入了一种基于LED的新型口腔护理设备,该设备集成了三种不同的波长:蓝色用于抗菌效果,绿色用于抗炎效果,红色用于预防和治疗应用。利用计算机断层扫描(CT)数据,获取上下牙弓轨迹,以设计符合牙弓自然曲率的柔性印刷电路板(FPCB)。FPCB上经过精心布局的LED可确保在整个口腔内实现均匀的光分布和优化的辐照度。本研究系统地确定了实现适当辐照度密度所需的最佳设计参数和操作条件,包括LED的放置、操作时间以及通过驱动电流和占空比进行的功率控制。研究结果展示了一种切实有效的方法,可克服当前LED口腔护理设备的局限性,显著提高其在牙科光疗中的性能和适用性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7655/11919360/86ca23474f07/boe-16-3-922-g011.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7655/11919360/d2310adf1c82/boe-16-3-922-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7655/11919360/e3d2485bfec0/boe-16-3-922-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7655/11919360/1cb8193e622b/boe-16-3-922-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7655/11919360/7721aecd3d87/boe-16-3-922-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7655/11919360/92f977d5b40f/boe-16-3-922-g009.jpg
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本文引用的文献

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Adjunctive effect of 470-nm and 630-nm light-emitting diode irradiation in experimental periodontitis treatment: a preclinical study.470纳米和630纳米发光二极管照射在实验性牙周炎治疗中的辅助作用:一项临床前研究。
J Periodontal Implant Sci. 2024 Feb;54(1):13-24. doi: 10.5051/jpis.2203580179. Epub 2023 May 9.
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Effects of blue-light LED toothbrush on reducing dental plaque and gingival inflammation in orthodontic patients with fixed appliances: a crossover randomized controlled trial.蓝光 LED 牙刷对固定矫治器正畸患者减少牙菌斑和牙龈炎症的效果:一项交叉随机对照试验。
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Repeated irradiation by light-emitting diodes may impede the spontaneous progression of experimental periodontitis: a preclinical study.
发光二极管反复照射可能会阻碍实验性牙周炎的自然进展:一项临床前研究。
J Periodontal Implant Sci. 2023 Apr;53(2):120-134. doi: 10.5051/jpis.2202320116. Epub 2022 Oct 11.
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investigation of the antibacterial and anti-inflammatory effects of LED irradiation.LED照射的抗菌和抗炎作用研究
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High-Intensity Red Light-Emitting Diode Irradiation Suppresses the Inflammatory Response of Human Periodontal Ligament Stem Cells by Promoting Intracellular ATP Synthesis.高强度红光发光二极管照射通过促进细胞内ATP合成抑制人牙周膜干细胞的炎症反应。
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Light-emitting-diode-based antimicrobial photodynamic therapies in the treatment of periodontitis.基于发光二极管的光动力抗菌疗法在牙周炎治疗中的应用。
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