Hashim Hashim Talib, Al-Obaidi Ahmed Dheyaa, Al-Obaidi Mustafa Najah, Ali Hossam Tharwat, Sula Idris, Alfaki Hozifa, Elamin Abdelrahim, Hermis Alaa Hamza, Othman Assalah, Alhatemi Ahmed Qasim Mohammed
College of Medicine Warith Al-Anbiyaa University Karbala Iraq.
College of Medicine University of Baghdad Baghdad Iraq.
Health Sci Rep. 2025 Mar 19;8(3):e70493. doi: 10.1002/hsr2.70493. eCollection 2025 Mar.
Systemic lupus erythematosus (SLE) is a recurrent and remitting autoimmune disease that affects many organ systems. It is more common in women of reproductive age, with a 9:1 female preponderance. Due to the lack of data from developing countries, our study aims to provide comprehensive insights into the drug history and SLE laboratory findings among Iraqi patients.
It is a cross-sectional study at the Baghdad Medical Complex in Iraq. All SLE patients who attended the outpatient clinic between September and December 2022 were included. The patients included those who came for follow-up, deterioration of their symptoms, or a first-time diagnosis.
SLE is much more prevalent among female patients. The ratio of female and male patients in our study was 19:1. This disease is more prevalent in the reproductive age group, with the mean age of our patients being 34 years, although the range spans from 15 to 85 years. The most prevalent signs and symptoms among the patients were photosensitivity (79.5%), hair loss (74%), and malar rash (72.5%). Most patients had positive antinuclear antibodies and anti-double-stranded DNA antibodies, with 73.5% and 65% testing positive, respectively.
In conclusion, this study represents an important step in exploring SLE within Iraq, providing invaluable insights into its management and laboratory findings. The findings contribute to the global understanding of SLE. This study underscores the significance of Iraq's genetic backgrounds and environmental conditions, which are different from those of other countries, in the process of enhancing the global medical literature and expanding our understanding of SLE patterns around the world.
系统性红斑狼疮（SLE）是一种反复发作和缓解的自身免疫性疾病，可累及多个器官系统。该病在育龄女性中更为常见，女性与男性的患病比例为9:1。由于缺乏来自发展中国家的数据，我们的研究旨在全面了解伊拉克患者的用药史和SLE实验室检查结果。
这是一项在伊拉克巴格达医疗中心进行的横断面研究。纳入了2022年9月至12月期间在门诊就诊的所有SLE患者。这些患者包括前来复诊、症状恶化或首次诊断的患者。
SLE在女性患者中更为普遍。我们研究中的女性和男性患者比例为19:1。这种疾病在育龄组中更为普遍，我们患者的平均年龄为34岁，尽管年龄范围跨度为15至85岁。患者中最常见的体征和症状是光敏性（79.5%）、脱发（74%）和蝶形红斑（72.5%）。大多数患者抗核抗体和抗双链DNA抗体呈阳性，分别有73.5%和65%检测呈阳性。
总之，本研究是在伊拉克探索SLE的重要一步，为其管理和实验室检查结果提供了宝贵的见解。这些发现有助于全球对SLE的理解。本研究强调了伊拉克不同于其他国家的遗传背景和环境条件在丰富全球医学文献以及扩展我们对世界各地SLE模式理解过程中的重要性。
