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新冠病毒暴露后患痴呆症、焦虑症和抑郁症风险的性别特异性人群研究。

Study on Gender-specific Population at Risk of Developing Dementia, Anxiety and Depression Following Exposure to COVID-19.

作者信息

Padhiar Jigar S, Rai Uddipak

机构信息

School of Pharmaceutical & Population Health Informatics, DIT University, Dehradun, Uttarakhand, India.

出版信息

Ann Neurosci. 2025 Mar 18:09727531251319838. doi: 10.1177/09727531251319838.

Abstract

BACKGROUND

The identification of COVID-19 first occurred in January 2020. The rapid transmission of this virus across human populations has led to the emergence of a global pandemic known as COVID-19. Dementia, anxiety and depression are neurological disorders that impact several higher cognitive functions, such as memory, cognition, orientation, understanding, computation, learning ability, language and decision-making.

PURPOSE

This study aims to examine the impact of demographic factors on the occurrence of dementia, anxiety and depression in individuals who have recovered from a COVID-19 infection.

METHODS

This study aims to investigate individuals who are at risk of developing dementia, anxiety and depression following exposure to COVID-19. Ethics Committee approval was obtained from hospital (Ethics Committee-Unique Hospital, Surat, India) and University Research Ethics Committee approval was obtained from Dehradun Institute of Technology University, Dehradun, India (DITU/UREC/2022/04/6). Patients willingly participated in the study and signed the ICF as per their preferred language. Patient data was obtained from the hospital with the assistance of medical staff. The study included patients who met the specific criteria for participation, as determined by the inclusion and exclusion criteria. Patients who satisfy the eligibility conditions were obligated to complete the questionnaire. The data was examined based on the subject's responses.

RESULTS

Exposure to COVID-19 has been linked to a heightened susceptibility to developing mental health issues, such as anxiety, depression and even dementia. Studies have demonstrated that persons who have acquired COVID-19 are more prone to developing various psychiatric disorders in comparison to those who have not been infected. Individuals with dementia encountered a decline in cognitive function and a rise in neuropsychiatric symptoms, including restlessness, confusion, irritability and lack of motivation, amidst the epidemic. Research has indicated that persons experiencing mild cognitive impairment or dementia exhibited elevated levels of despair and anxiety amongst the epidemic.

CONCLUSION

In this research study on the gender-specific effects of COVID-19 exposure on high-risk persons, development of dementia, anxiety and depression offers important new insights into the complex ways that the pandemic has affected mental health in different genders.

摘要

背景

2020年1月首次发现新型冠状病毒肺炎(COVID-19)。这种病毒在人群中的快速传播导致了一场名为COVID-19的全球大流行。痴呆症、焦虑症和抑郁症是影响多种高级认知功能的神经疾病,如记忆、认知、定向、理解、计算、学习能力、语言和决策。

目的

本研究旨在探讨人口统计学因素对从COVID-19感染中康复的个体发生痴呆症、焦虑症和抑郁症的影响。

方法

本研究旨在调查接触COVID-19后有患痴呆症、焦虑症和抑郁症风险的个体。已获得医院伦理委员会批准(印度苏拉特Unique医院伦理委员会),并获得印度德拉敦理工大学(印度德拉敦,DITU/UREC/2022/04/6)大学研究伦理委员会批准。患者自愿参与研究,并根据自己喜欢的语言签署知情同意书。患者数据是在医务人员的协助下从医院获得的。该研究纳入了符合纳入和排除标准所确定的特定参与标准的患者。符合资格条件的患者有义务完成问卷。根据受试者的回答对数据进行检查。

结果

接触COVID-19与患心理健康问题(如焦虑、抑郁甚至痴呆症)的易感性增加有关。研究表明,与未感染COVID-19的人相比,感染了该病毒的人更容易患上各种精神疾病。在疫情期间,患有痴呆症的个体认知功能下降,神经精神症状增加,包括坐立不安、困惑、易怒和缺乏动力。研究表明,在疫情期间,患有轻度认知障碍或痴呆症的人绝望和焦虑水平升高。

结论

在这项关于COVID-19暴露对高危人群的性别特异性影响的研究中,痴呆症、焦虑症和抑郁症的发生为大流行以复杂方式影响不同性别人群心理健康提供了重要的新见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb8a/11920980/502148de6bfb/10.1177_09727531251319838-fig1.jpg

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