Tiwari Harish Kumar, Tan Daniel K Y, Chinda Chhe, My Duong Nu Tra, Hoang Ha Thi Thu, Keonam Khao, Huong Luu Quynh, Chanvatanak Ly, Virak Mot, Tram Nguyen Thuy, Soulinthone Nittakone, Phuc Pham Duc, Nguyen Thi Thu Hoai, Tra Vu Thi Thu, Beardsley Justin
Sydney Medical School, Faculty of Medicine and Health, University of Sydney, NSW, Australia.
School of Health Science and Technology, Indian Institute of Technology Guwahati, Guwahati, Assam, India.
One Health. 2025 Feb 27;20:101001. doi: 10.1016/j.onehlt.2025.101001. eCollection 2025 Jun.
Antimicrobial resistance (AMR) has emerged as a significant global challenge and Southeast Asia with rapid economic and population growth faces substantial challenge in dealing with emerging infectious diseases and antimicrobial resistance. Here we present the recommendations of a workshop that explored the challenges and opportunities for One Health approach towards AMR research in three countries of AEAN, namely, Cambodia, Laos, and Vietnam.
A workshop was organised in Hanoi, Vietnam in August 2023, involving participants involved in AMR research across varied sectors from three participating countries to prioritise the strategies that can be implemented in the region to fructify the One Health approach to tackle AMR. A modified Delphi approach was used to prioritise the top 10 Global Priority Research Questions for the region as developed by the Quadripartite (FAO, WHO, WOAH and UNEP). An iterative process was adopted to map priorities according to their impact and feasibility of application.
Collaborative initiatives, such as a common platform for listing the research goals, a web-based surveillance mechanism, and an enhanced AMR awareness curricula were identified as the steps forward. A consensus statement highlighting the critical needs for improved technical and infrastructure capacity, collaboration between sectors, increased funding, and systematic data analysis was drafted.
The participating countries have National Action Plans guided by the World Health Organization's Global Action Plan on AMR, but limited collaboration between human health and other sectors has impeded the benefits that One Health approach may achieve in the region. The recommendations include the need for improved technical and infrastructure capacity, and data collection across One Health sectors, besides increasing awareness at multiple levels.
A collaborative and coordinated effort to apply One Health initiatives for tackling AMR in the ASEAN region is imperative. The workshop formulated a roadmap for future direction by identifying priorities aimed at enhancing collaboration, addressing infrastructure gaps, and contributing to an effective intervention in the fight against AMR in the region.
抗菌药物耐药性（AMR）已成为一项重大的全球挑战，随着经济和人口的快速增长，东南亚在应对新出现的传染病和抗菌药物耐药性方面面临巨大挑战。在此，我们介绍一个研讨会的建议，该研讨会探讨了东盟三个国家（柬埔寨、老挝和越南）在AMR研究中采用“同一健康”方法所面临的挑战和机遇。
2023年8月在越南河内举办了一次研讨会，来自三个参与国不同部门的AMR研究人员参与其中，以确定可在该地区实施的战略，以落实“同一健康”方法来应对AMR。采用改良的德尔菲法对四方（粮农组织、世界卫生组织、世界动物卫生组织和联合国环境规划署）制定的该地区前10个全球优先研究问题进行排序。采用迭代过程根据其影响和应用可行性来确定优先事项。
确定了一些合作举措，例如用于列出研究目标的共同平台、基于网络的监测机制以及强化的AMR意识课程。起草了一份共识声明，强调了提高技术和基础设施能力、部门间合作、增加资金以及系统数据分析的迫切需求。
参与国拥有由世界卫生组织《AMR全球行动计划》指导的国家行动计划，但人类健康与其他部门之间的合作有限，阻碍了“同一健康”方法在该地区可能实现的益处。建议包括除了在多个层面提高认识外，还需要提高技术和基础设施能力，并在“同一健康”各部门进行数据收集。
在东盟地区，必须共同协作、协调努力应用“同一健康”举措来应对AMR。该研讨会通过确定旨在加强合作、弥补基础设施差距以及为该地区有效干预AMR做出贡献的优先事项，制定了未来方向路线图。
