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摩洛哥女性乳腺癌的流行病学及临床结局:一项六年回顾性研究

Breast cancer epidemiology and clinical outcomes in Moroccan women: a six-year retrospective study.

作者信息

Aboulhoda Fatiha, Erefai Ouassima, Bejja Fadia, Soulaymani Abdelmajid, Mokhtari Abdelrhani, Hami Hinde

机构信息

Laboratory of Biology and Health, Faculty of Science, Ibn Tofail University, Kenitra, Morocco.

Higher Institute of Nursing Professions and Health Techniques, Rabat, Morocco.

出版信息

Pan Afr Med J. 2024 Dec 13;49:120. doi: 10.11604/pamj.2024.49.120.42588. eCollection 2024.

Abstract

INTRODUCTION

breast cancer is the most commonly diagnosed cancer among women in Morocco, with 11,747 new cases reported in 2020. This study aimed to provide a comprehensive overview of the epidemiological and clinical aspects of breast cancer in Moroccan women.

METHODS

this retrospective study included all female breast cancer patients diagnosed at the Reference Center for Reproductive Health in Kenitra from 2013 to 2018. A detailed analysis of the patients´ medical records was conducted in this study.

RESULTS

the study included 973 female participants. The mean age of the patients was 51.1 ± 12.3 years (range, 18-95 years). Notably, 65.1% of the participants were from urban areas. The median diagnosis delay was 8 days. Over half (53.3%) of the women were postmenopausal, with a mean age at menopause of 50.3 ± 4 years. The mean age at first pregnancy was 23.9 ± 6.8 years, ranging from 12 to 47 years. Fifty-four percent of the women used hormonal contraceptives, primarily oral pills. During clinical examination, breast nodules were the most prevalent presenting sign in the sampled women, with nodules typically found to be fixed in 89% of cases in the right breast and 91% in the left breast.

CONCLUSION

the study revealed significant concerns regarding women diagnosed at the Reference Center for Reproductive Health in Kenitra, such as prolonged diagnosis delays, advanced age at menopause, and a considerable prevalence of nodules and palpable axillary adenopathy.

摘要

引言

乳腺癌是摩洛哥女性中最常被诊断出的癌症,2020年报告了11747例新病例。本研究旨在全面概述摩洛哥女性乳腺癌的流行病学和临床方面。

方法

这项回顾性研究纳入了2013年至2018年在凯尼特拉生殖健康参考中心诊断出的所有女性乳腺癌患者。本研究对患者的病历进行了详细分析。

结果

该研究纳入了973名女性参与者。患者的平均年龄为51.1±12.3岁(范围为18至95岁)。值得注意的是,65.1%的参与者来自城市地区。中位诊断延迟为8天。超过一半(53.3%)的女性已绝经,绝经的平均年龄为50.3±4岁。首次怀孕的平均年龄为23.9±6.8岁,范围为12至47岁。54%的女性使用激素避孕药,主要是口服避孕药。在临床检查中,乳腺结节是抽样女性中最常见的体征,在右侧乳房中89%的病例结节通常固定,左侧乳房中91%的病例结节通常固定。

结论

该研究揭示了在凯尼特拉生殖健康参考中心被诊断出的女性存在的重大问题,如诊断延迟延长、绝经年龄较大以及结节和可触及腋窝淋巴结病的患病率相当高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f1a/11928303/df4eea9c3098/PAMJ-49-120-g001.jpg

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