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针对年轻成年人的数字皮肤癌风险降低干预措施:一项混合型II期有效性-实施试验的结果

Digital Skin Cancer Risk Reduction Interventions for Young Adults: Findings from a Hybrid Type-II Effectiveness-Implementation Trial.

作者信息

Heckman Carolyn J, Handorf Elizabeth A, Mitarotondo Anna, Khavjou Olga, Manne Sharon L, Yaroch Amy L, Glanz Karen

机构信息

Cancer Prevention and Control Program, Rutgers Cancer Institute, New Brunswick, New Jersey.

Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, New Jersey.

出版信息

Cancer Epidemiol Biomarkers Prev. 2025 Jun 3;34(6):962-971. doi: 10.1158/1055-9965.EPI-24-1636.

Abstract

BACKGROUND

Engagement in sun protection behaviors is low among young adults (ages 18-25 years). Efficacious sun safety interventions for this at-risk population and information on intervention engagement and costs are needed. The purpose was to conduct secondary analyses examining intervention implementation strategies and outcomes (e.g., engagement), intervention moderators, and costs of three digital interventions to increase sun protection behaviors previously evaluated for effectiveness in a randomized controlled trial.

METHODS

The randomized controlled trial compared three conditions: a basic efficacious intervention, an enhanced version of the intervention, and an educational e-pamphlet. Sun protection measures, intervention engagement and implementation, putative moderators, and intervention costs were assessed through 1 year.

RESULTS

Engagement (4.6 of 12 modules completed) was similar for basic and enhanced interventions. Engagement was significantly associated with sun protection. Men and individuals with lower tanning ability completed more modules than women and those with higher tanning ability. Enhanced was more effective than basic for men (but not women) through 1 year. After initial development, both active interventions were similar in cost per person at larger sample sizes.

CONCLUSIONS

Despite attempts at enhancement, engagement in basic and enhanced was similar. Although all interventions were costly to create, they were less costly to maintain and could be scaled up for dissemination. Based on both engagement and effects on sun protection, the enhanced intervention would be recommended for men, women, or both.

IMPACT

This digital intervention offers the potential to reduce skin cancer risk in a large population of US young adults.

摘要

背景

在年轻人(18 - 25岁)中,采取防晒行为的比例较低。对于这一高危人群,需要有效的防晒干预措施以及关于干预参与情况和成本的信息。目的是进行二次分析,以检验三种数字干预措施的实施策略和结果(如参与情况)、干预调节因素以及成本,这三种干预措施此前在一项随机对照试验中已评估过其有效性,旨在增加防晒行为。

方法

随机对照试验比较了三种情况:一种基本有效的干预措施、该干预措施的增强版本以及一份教育电子宣传册。通过一年时间评估防晒措施、干预参与和实施情况、假定的调节因素以及干预成本。

结果

基本干预措施和增强干预措施的参与度(完成12个模块中的4.6个)相似。参与度与防晒显著相关。男性和晒黑能力较低的个体比女性和晒黑能力较高的个体完成的模块更多。在长达一年的时间里,增强干预措施对男性(而非女性)比基本干预措施更有效。在初步开发之后,在更大样本量的情况下,两种主动干预措施的人均成本相似。

结论

尽管进行了增强尝试,但基本干预措施和增强干预措施的参与度相似。虽然所有干预措施的创建成本都很高,但维护成本较低,并且可以扩大规模进行推广。基于参与度和对防晒的效果,增强干预措施对男性、女性或两者都推荐使用。

影响

这种数字干预措施有可能降低大量美国年轻人患皮肤癌的风险。

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