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土耳其语版多发性硬化症核心下尿路症状评分的信度和效度

Reliability and validity of the Turkish version of the core lower urinary tract symptom score in multiple sclerosis.

作者信息

Kiloatar Humeyra, Delibay Aylin Aydogdu, Demir Cimen Olçay, Ceylan Dursun, Uysal Niyazi

机构信息

Department of Physiotherapy and Rehabilitation, Faculty of Health Science, Kutahya Health Sciences University, Campus of Germiyan, 43100, Kutahya, Turkey.

Department of Neurology, Faculty of Medicine, Kutahya Health Sciences University, Campus of Germiyan, 43100, Kutahya, Turkey.

出版信息

Acta Neurol Belg. 2025 Mar 26. doi: 10.1007/s13760-025-02769-0.

DOI:10.1007/s13760-025-02769-0
PMID:40133731
Abstract

BACKGROUND

In multiple sclerosis, lower urinary tract symptoms are frequently observed depending on the site of involvement. A comprehensive assessment of these symptoms is crucial for their effective management.

OBJECTIVE

This research was designed to evaluate the validity and reliability of the Turkish adaptation of the Core Lower Urinary Tract Symptom Scale (CLSS) in patients with multiple sclerosis (PwMS).

METHODS

71 PwMS who had an Expanded Disability Status Scale score of 6.5 or below was included. Data collection involved demographic information as well as responses to the CLSS, Overactive Bladder Questionnaire, Interstitial Cystitis Symptom Index, Interstitial Cystitis Problem Index, and International Prostate Symptom Score. To evaluate test-retest reliability, the CLSS was administered again under identical conditions after a 7-day interval.

RESULTS

The internal consistency of the questionnaire was assessed, resulting in a Cronbach's alpha coefficient of 0.79. Test-retest reliability for the CLSS sub-items ranged from 0.593 to 0.950. No statistically significant differences were found between the sub-items scores of the test and retest administrations. (p > 0.05). Moreover, the subscales showed significant correlations with the other questionnaires, with correlation coefficients varying between 0.109 and 0.770. Straining, feeling incomplete emptying, and pain in the bladder sub-items did not show a significant correlation with the corresponding sub-items of other questionnaires (r = 0.109, 0.270, and 0.195, respectively).

CONCLUSION

The Turkish adaptation of the CLSS questionnaire has been proven to be a reliable and valid instrument for evaluating lower urinary tract symptoms in PwMS.

CLINICALTRIALS

Gov Number: NCT06599866.

摘要

背景

在多发性硬化症中,根据受累部位经常观察到下尿路症状。对这些症状进行全面评估对于有效管理至关重要。

目的

本研究旨在评估核心下尿路症状量表(CLSS)土耳其语版在多发性硬化症患者(PwMS)中的有效性和可靠性。

方法

纳入71例扩展残疾状态量表评分在6.5或以下的PwMS。数据收集包括人口统计学信息以及对CLSS、膀胱过度活动症问卷、间质性膀胱炎症状指数、间质性膀胱炎问题指数和国际前列腺症状评分的回答。为评估重测信度,在间隔7天后在相同条件下再次进行CLSS测试。

结果

评估了问卷的内部一致性,Cronbach's alpha系数为0.79。CLSS子项目的重测信度范围为0.593至0.950。测试和重测管理的子项目得分之间未发现统计学上显著差异(p>0.05)。此外,各子量表与其他问卷显示出显著相关性,相关系数在0.109至0.770之间变化。用力排尿、感觉排空不完全和膀胱子项目疼痛与其他问卷的相应子项目未显示出显著相关性(r分别为0.109、0.270和0.195)。

结论

CLSS问卷的土耳其语版已被证明是评估PwMS下尿路症状的可靠且有效的工具。

临床试验

政府编号:NCT06599866。

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本文引用的文献

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Impact on quality of life in multiple sclerosis patients: Which urinary symptoms are to blame?多发性硬化症患者生活质量的影响:哪些尿路症状是罪魁祸首?
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多发性硬化症患者下尿路症状的患病率:一项系统评价和荟萃分析。
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Core Lower Urinary Tract Symptom score (CLSS) questionnaire: a reliable tool in the overall assessment of lower urinary tract symptoms.下尿路症状核心评分(CLSS)问卷:下尿路症状综合评估中的可靠工具。
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