Glickman L T, Schantz P M
Z Parasitenkd. 1985;71(3):395-400. doi: 10.1007/BF00928341.
A variety of helminth parasites have A and B blood group antigens on their surface. These antigens may cross-react with elevated concentrations of A and B isohemagglutinins in some patients and give false-positive results in the serologic diagnosis of visceral larva migrans caused by T. canis. To clarify this point, serum from patients with visceral larva migrans and elevated T. canis antibody titers as determined by ELISA were absorbed with AB blood cells and retested by ELISA without a demonstrable decline in T. canis antibody titers. Similarly, absorption with T. canis embryonated egg antigens of serum containing elevated levels of anti-A or anti-B isohemagglutinins failed to decrease the isohemagglutinin titer. This indicates that the ELISA using T. canis embryonated egg antigen does not give false positive results with sera containing high concentrations of anti-A or anti-B isohemagglutinins.
多种蠕虫寄生虫在其表面具有A和B血型抗原。这些抗原可能与某些患者中升高的A和B同种血凝素浓度发生交叉反应，并在犬弓首线虫引起的内脏幼虫移行症的血清学诊断中给出假阳性结果。为了阐明这一点，用AB血细胞吸收经ELISA测定的内脏幼虫移行症患者且犬弓首线虫抗体滴度升高的血清，然后通过ELISA重新检测，犬弓首线虫抗体滴度没有明显下降。同样，用含有高水平抗A或抗B同种血凝素的血清与犬弓首线虫感染性虫卵抗原进行吸收，未能降低同种血凝素滴度。这表明使用犬弓首线虫感染性虫卵抗原的ELISA不会对含有高浓度抗A或抗B同种血凝素的血清产生假阳性结果。
