Reĭzis A R, Drondina A N, Aspatian A A, Ivanova M Iu, Kozhevnikova L K
Zh Mikrobiol Epidemiol Immunobiol. 1985 Apr(4):48-51.
A total of 231 persons from the families of 62 children hospitalized in connection with viral hepatitis B were examined for the presence of HBsAg in their blood over a period of 3 years. Simultaneously with countercurrent electrophoresis (CIE) and the gel precipitation (GP) test, the passive hemagglutination (PHA) test and the GP test with sandwich treatment were used in this work. The presence of HBs-antigenemia in the members of the families of children with viral hepatitis confirmed by laboratory methods were found to occur 6.7 times more frequently than in the families of children with HBsAg-negative hepatitis. The use of the PHA test and the GP test with sandwich treatment increased the frequency of the detection of HBsAg 2.5 times in comparison with CIE and the GP test. The data indicating the possibility of children being infected through everyday contacts in families with cases of HBs-antigenemia among their members are presented, but further studies are necessary to make the final decision on this problem.
在3年时间里，对因乙型病毒性肝炎住院的62名儿童家庭中的231人进行了血液中乙肝表面抗原（HBsAg）检测。本研究同时采用了对流免疫电泳（CIE）、凝胶沉淀试验（GP）、被动血凝试验（PHA）以及夹心处理的GP试验。通过实验室方法确诊的病毒性肝炎患儿家庭成员中乙肝表面抗原血症的出现频率，是乙肝表面抗原阴性肝炎患儿家庭的6.7倍。与CIE和GP试验相比，PHA试验和夹心处理的GP试验使HBsAg的检测频率提高了2.5倍。文中给出的数据表明，家庭成员中有乙肝表面抗原血症病例的家庭中，儿童有可能通过日常接触而感染，但要就这一问题做出最终决定，还需要进一步研究。
