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夜间工作与社会时差:通往动脉僵硬的途径?

Night Work and Social Jet Lag: Pathways to Arterial Stiffness?

作者信息

Gusmão Waléria D P, Silva-Costa Aline, Silva Victor M, Moreno Claudia R C

机构信息

Center for Integrative Sciences, Alagoas State University of Health Sciences (UNCISAL), Maceio 57010-382, Brazil.

Department of Collective Health, Federal University of Triangulo, Mineiro, Uberaba 38025-350, Brazil.

出版信息

Clocks Sleep. 2025 Mar 3;7(1):10. doi: 10.3390/clockssleep7010010.

Abstract

Cardiovascular diseases are the leading cause of morbidity and mortality worldwide. These conditions, characterized by multifactorial etiology, are associated with arterial stiffness, and adequate sleep serves as a preventive factor. Professionals engaged in night work are at an increased risk of premature vascular aging due to potential disruption of the sleep-wake cycle and sleep restriction. The aim of this study was to assess the relationship between duration of exposure to night work and arterial stiffness in nursing professionals. A total of 63 nursing professionals working rotating shifts participated in the study. Arterial stiffness was measured using oscillometric pulse wave velocity, and sleep-wake patterns were monitored using actigraphy. Path analysis revealed no direct association between duration of night work exposure and arterial stiffness in the professionals studied. However, an increase of 1 standard deviation (SD) in social jet lag duration was significantly associated with a 0.212 SD increase in perceived stress ( = 0.047). Furthermore, an increase of 1 SD in social jet lag duration was significantly associated with a 0.093 SD increase in the highest pulse wave velocity ( = 0.034). Thus, an association was found between increased social jet lag and elevated pulse wave velocity, an independent predictor of higher cardiovascular risk.

摘要

心血管疾病是全球发病和死亡的主要原因。这些疾病病因多因素,与动脉僵硬度有关,充足睡眠是一个预防因素。从事夜班工作的专业人员由于睡眠-觉醒周期可能被打乱以及睡眠受限,血管过早老化的风险增加。本研究的目的是评估护理专业人员夜班工作暴露时长与动脉僵硬度之间的关系。共有63名轮班工作的护理专业人员参与了该研究。使用示波法脉搏波速度测量动脉僵硬度,使用活动记录仪监测睡眠-觉醒模式。路径分析显示,在所研究的专业人员中,夜班工作暴露时长与动脉僵硬度之间无直接关联。然而,社会时差时长每增加1个标准差(SD),感知压力显著增加0.212个标准差(P = 0.047)。此外,社会时差时长每增加1个标准差,最高脉搏波速度显著增加0.093个标准差(P = 0.034)。因此,发现社会时差增加与脉搏波速度升高之间存在关联,脉搏波速度升高是心血管风险增加的一个独立预测因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143d/11941686/b996120ea306/clockssleep-07-00010-g001.jpg

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