Pretorius Isak S, Dixon Thomas A, Boers Michael, Paulsen Ian T, Johnson Daniel L
ARC Centre of Excellence in Synthetic Biology, Macquarie University, Sydney, Australia.
Silicon Platforms Laboratory, Macquarie University, Sydney, NSW, Australia.
Nat Commun. 2025 Mar 26;16(1):2959. doi: 10.1038/s41467-025-58030-y.
Information and energy flows form the basis of all economic activity, with advanced technologies underpinning both. Profound uncertainties caused by geostrategic forces have accelerated a trillion-dollar race for technological superiority. The result is an onrush of "technovation" at the nexus of synthetic biotechnologies, information technologies, nanotechnologies and engineering technologies. This article explores recent breakthroughs in integrating chip technologies and synthetic bioinformational engineering. It investigates prospects of biomolecules as carriers of stored digital data, synthetic cells-on-a-chip, and hybrid semiconductors and next-generation artificial intelligence processors. Consilience-unity of knowledge-redefines possibilities emerging from the living interface of biologically-inspired engineering and engineering-enabled biology.
信息和能量流动构成了所有经济活动的基础,先进技术是两者的支撑。地缘战略力量造成的深度不确定性加速了一场万亿美元的技术优势竞赛。其结果是在合成生物技术、信息技术、纳米技术和工程技术的交叉点上出现了 “技术创新” 的热潮。本文探讨了芯片技术与合成生物信息工程整合方面的最新突破。它研究了生物分子作为存储数字数据的载体、芯片上的合成细胞以及混合半导体和下一代人工智能处理器的前景。知识的一致性 —— 统一 —— 重新定义了受生物启发的工程与工程赋能的生物学的生命界面所产生的可能性。