Zhang QingSha, Liu HongKun, Sun Jie, Shi HongGe
Department of Rehabilitation Medicine, Zibo Central Hospital, No. 54 Communist Youth League West Road, Zhangdian District, Zibo City, 255000, Shandong Province, China.
Department of Integrative Medicine and Orthopaedics, Zibo Central Hospital, Zibo City, 255000, Shandong Province, China.
Eur J Med Res. 2025 Mar 26;30(1):208. doi: 10.1186/s40001-025-02451-4.
This study investigated the effect of a comprehensive pulmonary rehabilitation (CPR) program on stroke-associated pneumonia (SAP) in patients with moderate-to-severe acute ischemic stroke (AIS) after thrombolysis.
This study was a prospective randomized controlled intervention study. Eighty patients with moderate-to-severe AIS were divided into the conventional rehabilitation (CR) and CPR groups. Demographic and general clinical data were collected. Patients were evaluated by the Fatigue Severity Scale (FSS), Fugl-Meyer Assessment (FMA), and Fugl-Meyer balance (FMB). The incidence of pneumonia in the acute phase and the treatment efficacy were compared.
FSS scores at T1 and T2 (2 weeks and 4 weeks after treatment), FMA scores, and FMB scores were higher than those at T0 (first day of admission). FSS scores in the CPR group were lower, while FMA and FMB scores were higher than those in the CR group at T1 and T2. The incidence of pneumonia was 10.00% in the CPR group and 25.00% in the CR group. The rehabilitation effective rate was 92.50% in the CPR group and 80.00% in the CR group, but the proportion of rehabilitation effect in the CPR group was higher than that in the CR group.
CPR program improves fatigue and motor function and reduces the occurrence of SAP in AIS patients.
本研究探讨了综合肺康复（CPR）方案对中重度急性缺血性卒中（AIS）溶栓后患者卒中相关性肺炎（SAP）的影响。
本研究为前瞻性随机对照干预研究。80例中重度AIS患者被分为传统康复（CR）组和CPR组。收集人口统计学和一般临床资料。采用疲劳严重程度量表（FSS）、Fugl-Meyer评估（FMA）和Fugl-Meyer平衡量表（FMB）对患者进行评估。比较急性期肺炎的发生率和治疗效果。
T1和T2（治疗后2周和4周）时的FSS评分、FMA评分和FMB评分均高于T0（入院首日）。在T1和T2时，CPR组的FSS评分较低，而FMA和FMB评分高于CR组。CPR组肺炎发生率为10.00%，CR组为25.00%。CPR组康复有效率为92.50%，CR组为80.00%，但CPR组康复效果比例高于CR组。
CPR方案可改善AIS患者的疲劳和运动功能，并减少SAP的发生。
