Successful Pregnancy after Fertility-sparing Surgery and Treatment for Metachronous Multiple Primary Malignancies - A Case Report.

The occurrence of metachronous multiple primary malignancies remains relatively rare; however, its incidence is notably rising. We present the case of a 25-year-old woman who underwent fertility-sparing surgery, followed by chemotherapy for ovarian yolk sac tumor. Three years later, the patient was diagnosed with a large B-cell lymphoma in the cecum. She underwent bowel surgery and received chemotherapy postoperatively. Despite her condition, she was able to conceive spontaneously and had a successful pregnancy after treatment. This report highlights the importance of considering fertility-preserving treatment strategies in young patients and the possibility of spontaneous conception and successful pregnancy even in patients diagnosed with metachronous multiple primary malignancies who underwent extensive surgical procedures and heavily treated with chemotherapy.