Ko Yeon-Kyoung, Lee Seung-Bo, Lee Si-Wook
Department of Brain and Cognitive Engineering, Korea University, Seoul, South Korea.
Department of Medical Informatics, Keimyung University School of Medicine, Daegu, South Korea.
PLoS One. 2025 Mar 27;20(3):e0317251. doi: 10.1371/journal.pone.0317251. eCollection 2025.
Developmental Dysplasia of the Hip (DDH) is a relatively common hip joint disorders in infants, affecting one to three per a thousand births. If found early, it can be treated preemptively by simple non-invasive methods. But if not, then several surgical procedures may be required that can cause high economic burden. The accuracy of diagnosis using ultrasound (US) images heavily relies on locating anatomical landmarks on the image. However, there is an intra-observer/inter-observer variability in determining the exact location of the landmarks. In this study, an automated scan quality assessment system of pelvic US image by evaluating quality of five landmarks using transfer learning models was proposed.
US images from 1,891 subjects were obtained at two hospitals in the Republic of Korea (henceforth Korea). Also, an ensemble system was developed using transfer learning models to automatically evaluate the scan quality by scoring five anatomical landmarks. Gradient-weighted class activation mapping was used for verifying whether models that reflect the geographical features of the images had been properly trained. Considering the applicability in the real-time environment, this study proposes an alternative sequence method (ASM) that has been discovered to have improved the lapse of scan quality assessment.
All the selected models achieved kappa values of 0.6 or higher, indicating substantial agreement, and the AUC score for classifying standard images based on the total score was 0.89. The activation map of the trained models properly reflected the structural features of the image. The time lapse for standard image classification was 0.35 second per image in full sequence method, and that of the three versions - ASM-1, ASM-2, ASM-3 - were 0.27, 0.22, and 0.20, respectively.
发育性髋关节发育不良(DDH)是婴儿中较为常见的髋关节疾病,每千例出生中约有1至3例受影响。如果早期发现,可以通过简单的非侵入性方法进行预防性治疗。但如果未早期发现,则可能需要进行多次手术,这会带来高昂的经济负担。使用超声(US)图像进行诊断的准确性在很大程度上依赖于在图像上定位解剖标志。然而,在确定这些标志的确切位置时,存在观察者内/观察者间的变异性。在本研究中,提出了一种通过使用迁移学习模型评估五个标志的质量来自动评估骨盆超声图像扫描质量的系统。
从韩国的两家医院获取了1891名受试者的超声图像。此外,还开发了一个使用迁移学习模型的集成系统,通过对五个解剖标志进行评分来自动评估扫描质量。使用梯度加权类激活映射来验证反映图像地理特征的模型是否得到了正确训练。考虑到在实时环境中的适用性,本研究提出了一种替代序列方法(ASM),已发现该方法改善了扫描质量评估的时间间隔。
所有选定模型的kappa值均达到0.6或更高,表明具有实质性一致性,基于总分对标准图像进行分类的AUC分数为0.89。训练模型的激活图正确反映了图像的结构特征。全序列方法中标准图像分类的时间间隔为每张图像0.35秒,而三个版本——ASM-1、ASM-2、ASM-3——的时间间隔分别为0.27、0.22和0.20秒。