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对用于 COVID-19 患者肺部小数据集的十一种神经网络架构进行比较分析,以改善临床决策。

A comparative analysis of eleven neural networks architectures for small datasets of lung images of COVID-19 patients toward improved clinical decisions.

机构信息

Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, School of Medicine and Engineering, No.37 Xueyuan Road, Haidian District, Beijing, China; Key Laboratory of Big Data-Based Precision Medicine, Ministry of Industry and Information Technology, No.37 Xueyuan Road, Haidian District, Beijing, China; School of Automation Science and Electrical Engineering, Beihang University, No.37 Xueyuan Road, Haidian District, Beijing, China.

Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, School of Medicine and Engineering, No.37 Xueyuan Road, Haidian District, Beijing, China; Key Laboratory of Big Data-Based Precision Medicine, Ministry of Industry and Information Technology, No.37 Xueyuan Road, Haidian District, Beijing, China; School of Automation Science and Electrical Engineering, Beihang University, No.37 Xueyuan Road, Haidian District, Beijing, China.

出版信息

Comput Biol Med. 2021 Dec;139:104887. doi: 10.1016/j.compbiomed.2021.104887. Epub 2021 Sep 24.

Abstract

The 2019 novel severe acute respiratory syndrome coronavirus 2-SARS-CoV2, commonly known as COVID-19, is a highly infectious disease that has endangered the health of many people around the world. COVID-19, which infects the lungs, is often diagnosed and managed using X-ray or computed tomography (CT) images. For such images, rapid and accurate classification and diagnosis can be performed using deep learning methods that are trained using existing neural network models. However, at present, there is no standardized method or uniform evaluation metric for image classification, which makes it difficult to compare the strengths and weaknesses of different neural network models. This paper used eleven well-known convolutional neural networks, including VGG-16, ResNet-18, ResNet-50, DenseNet-121, DenseNet-169, Inception-v3, Inception-v4, SqueezeNet, MobileNet, ShuffeNet, and EfficientNet-b0, to classify and distinguish COVID-19 and non-COVID-19 lung images. These eleven models were applied to different batch sizes and epoch cases, and their overall performance was compared and discussed. The results of this study can provide decision support in guiding research on processing and analyzing small medical datasets to understand which model choices can yield better outcomes in lung image classification, diagnosis, disease management and patient care.

摘要

2019 年新型严重急性呼吸系统综合征冠状病毒 2(通常称为 COVID-19)是一种高度传染性疾病,已危及世界各地许多人的健康。COVID-19 感染肺部,通常使用 X 射线或计算机断层扫描(CT)图像进行诊断和管理。对于此类图像,可以使用经过现有神经网络模型训练的深度学习方法进行快速准确的分类和诊断。然而,目前对于图像分类还没有标准化的方法或统一的评估指标,这使得很难比较不同神经网络模型的优缺点。本文使用了十一种著名的卷积神经网络,包括 VGG-16、ResNet-18、ResNet-50、DenseNet-121、DenseNet-169、Inception-v3、Inception-v4、SqueezeNet、MobileNet、ShuffleNet 和 EfficientNet-b0,对 COVID-19 和非 COVID-19 肺部图像进行分类和区分。将这十一种模型应用于不同的批量大小和时期案例,并对其整体性能进行了比较和讨论。本研究的结果可以为处理和分析小医学数据集提供决策支持,以了解在肺部图像分类、诊断、疾病管理和患者护理中,哪种模型选择可以产生更好的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7373/8461289/4d023460e61d/gr1_lrg.jpg

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