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准备进行肝移植的小儿胆道闭锁患者的营养管理

Nutritional Management for Pediatric Biliary Atresia Patients Preparing for Liver Transplantation.

作者信息

Choe Uyory

机构信息

Department of Food and Nutrition, College of Biomedical and Health Science, Konkuk University, Chungju 27478, Republic of Korea.

出版信息

Children (Basel). 2025 Mar 20;12(3):391. doi: 10.3390/children12030391.

Abstract

Biliary atresia, a rare pediatric liver condition, results in blocked bile ducts, impeding bile secretion and causing significant nutritional challenges. This perspective emphasizes the critical role of nutrition in supporting children with biliary atresia awaiting liver transplantation. The liver's multifaceted functions in energy metabolism, vitamin storage, and waste excretion emphasize the importance of tailored dietary interventions. Medium-chain triglyceride (MCT) oil serves as a crucial energy source, addressing fat malabsorption, while specialized water-soluble formulations deliver essential fat-soluble vitamins. Additionally, weaning strategies and developmental food practices are discussed to ensure optimal growth and development despite dietary restrictions. Feeding assistance through nasogastric or gastrostomy tubes is explored as a means to combat malnutrition and support liver function. The collective efforts of caregivers and healthcare providers are pivotal in preparing these children for successful liver transplantation, aiming to secure their future health and quality of life.

摘要

胆道闭锁是一种罕见的儿科肝脏疾病,会导致胆管堵塞,阻碍胆汁分泌,并引发严重的营养挑战。本文强调了营养在支持等待肝移植的胆道闭锁患儿方面的关键作用。肝脏在能量代谢、维生素储存和废物排泄方面具有多方面功能,这凸显了量身定制饮食干预措施的重要性。中链甘油三酯(MCT)油是一种关键的能量来源,可解决脂肪吸收不良问题,而特殊的水溶性制剂可提供必需的脂溶性维生素。此外,还讨论了断奶策略和适合发育阶段的饮食做法,以确保尽管有饮食限制,患儿仍能实现最佳生长发育。探讨了通过鼻胃管或胃造口管提供喂养辅助,作为对抗营养不良和支持肝功能的一种手段。照顾者和医疗保健提供者的共同努力对于让这些患儿为成功进行肝移植做好准备至关重要,目标是确保他们未来的健康和生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c322/11941163/a88d8f325571/children-12-00391-g001.jpg

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