Internal Medicine & Hepatology Section, Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties-PROMISE, University of Palermo Medical School, 90127 Palermo, Italy.
Institute for Biochemical Research and Innovation, National Research Council (CNR), 90146 Palermo, Italy.
Nutrients. 2021 Nov 10;13(11):4014. doi: 10.3390/nu13114014.
Over the past few years, growing interest has been shown for the impact of dietary requirements and nutritional factors on chronic diseases. As a result, nutritional programs have been reinforced by public health policies. The precise role of micronutrients in chronic liver disease is currently receiving particular attention since abnormalities in vitamin levels are often detected. At present, treatment programs are focused on correcting vitamin deficiencies, which are frequently correlated to higher rates of comorbidities with poor outcomes. The literature reviewed here indicates that liver diseases are often related to vitamin disorders, due to both liver impairment and abnormal intake. More specific knowledge about the role of vitamins in liver disease is currently emerging from various results and recent evidence. The most significant benefits in this area may be observed when improved vitamin intake is combined with a pharmacological treatment that may also affect the progression of the liver disease, especially in the case of liver tumors. However, further studies are needed.
在过去的几年中，人们对饮食需求和营养因素对慢性疾病的影响表现出越来越大的兴趣。因此，营养计划得到了公共卫生政策的加强。由于经常检测到维生素水平异常，因此目前人们特别关注微量营养素在慢性肝病中的作用。目前，治疗方案主要集中在纠正维生素缺乏症上，因为维生素缺乏症通常与更高的并发症发生率和不良预后相关。这里回顾的文献表明，由于肝脏损伤和异常摄入，肝脏疾病通常与维生素紊乱有关。从各种结果和最近的证据中可以更清楚地了解维生素在肝脏疾病中的作用。当改善维生素摄入与可能影响肝脏疾病进展的药物治疗相结合时，在这一领域可能会观察到最大的益处，特别是在肝脏肿瘤的情况下。但是，还需要进一步的研究。
