英国镉作业工人的前列腺癌、慢性呼吸道疾病和肾脏疾病：一项病例对照研究。
Prostatic cancer and chronic respiratory and renal disease in British cadmium workers: a case control study.
作者信息
Armstrong B G, Kazantzis G
出版信息
Br J Ind Med. 1985 Aug;42(8):540-5. doi: 10.1136/oem.42.8.540.
Abstract
Deaths due to prostatic cancer, renal cancer, bronchitis or emphysema, and nephritis or nephrosis in three cohorts of cadmium workers have been investigated in a case-control study. Evidence of an association of risk for these diseases with intensity and duration of exposure to cadmium was sought. The only clearly statistically significant finding was of an association of deaths coded as bronchitis or emphysema with "high" levels of exposure to cadmium fume, which was related also to duration of exposure. There was suggestive evidence also (p congruent to 0.10) of an increased risk for nephritis or nephrosis after high exposure. Marginally increased risks were observed for prostatic cancer after high or "medium" exposure, but these were not statistically significant.
摘要
在一项病例对照研究中，对三组镉作业工人中因前列腺癌、肾癌、支气管炎或肺气肿以及肾炎或肾病导致的死亡情况进行了调查。研究旨在寻找这些疾病的风险与镉暴露强度和持续时间之间存在关联的证据。唯一在统计学上有明显显著意义的发现是，编码为支气管炎或肺气肿的死亡与“高”水平的镉烟暴露有关，这也与暴露持续时间有关。也有提示性证据（p值约为0.10）表明，高暴露后患肾炎或肾病的风险增加。高暴露或“中等”暴露后前列腺癌的风险略有增加，但这些在统计学上并不显著。
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