Agreements and Disagreements Between Professionals and Users About the Experience of a Telehealth Service for HIV Pre-Exposure Prophylaxis (TelePrEP): Qualitative Interview Study.

BACKGROUND

Men who have sex with men have a disproportionately high prevalence of HIV worldwide. In Brazil, men who have sex with men account for over 15% of HIV cases, substantially higher than the general population prevalence of 0.6%. Pre-exposure prophylaxis (PrEP) is a critical biomedical strategy for reducing HIV transmission, yet adherence remains challenging due to stigma, logistical barriers, and the need for regular clinical follow-ups. TelePrEP, a telehealth-based approach to PrEP follow-up, has emerged as a potential solution to improve accessibility and reduce stigma. However, the perspectives of users and health care providers on this intervention remain understudied in low- and middle-income countries, such as Brazil.

OBJECTIVE

This study aims to examine the experiences and perceptions of users and health care professionals regarding TelePrEP, an asynchronous remote consultation model, in 5 PrEP services across 3 Brazilian regions (southeast, south, and northeast).

METHODS

We conducted 19 in-depth interviews with PrEP users (aged between 23 and 58 years) and 6 interviews with health care professionals (aged between 35 and 61 years). Users were recruited from 5 public health care services, including outpatient HIV clinics and testing centers. The interviews explored motivations for PrEP use, experiences with in-person and remote consultations, perceived advantages and disadvantages of TelePrEP, and overall satisfaction. Thematic analysis was conducted using NVivo software.

RESULTS

Users reported greater convenience, increased autonomy, and reduced stigma, highlighting that the remote consultations eliminated the discomfort of discussing personal topics in person and minimized the need for frequent visits to health care facilities. Many felt that TelePrEP simplified HIV prevention, normalized PrEP use, and contributed to more sustainable adherence while also expressing confidence that periodic laboratory testing was sufficient for monitoring their health. Conversely, health care professionals raised concerns about the loss of personal connection with users, which they perceived as essential for detecting health issues and ensuring PrEP adherence. They also noted that TelePrEP could hinder the identification of sexually transmitted infections due to the absence of direct clinical assessments, and some questioned whether TelePrEP compromised the quality of care, fearing that users might delay reporting symptoms or other health concerns.

CONCLUSIONS

To effectively address the needs of both groups, the successful implementation of telehealth PrEP services must consider these differing perceptions. Further research is essential to explore implementation in diverse settings and enhance the training of health care professionals to address the specific requirements of PrEP care.