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多糖骨骼系统的物理化学性质、生物活性、应用及保护潜力:综述

Physicochemical properties, biological activities, applications, and protective potential of the skeletal system of polysaccharides: a review.

作者信息

Liu Xudong, Xing Yan, Liu Guijun, Bao Dapeng, Zhang Zhaojiong, Bi Haizheng, Wang Meng

机构信息

Heilongjiang University of Chinese Medicine, Key Laboratory of Basic and Application Research of Beiyao Ministry of Education, Harbin, China.

Nursing Humanities Teaching and Research Office, Heilongjiang Nursing College, Harbin, China.

出版信息

Front Pharmacol. 2025 Mar 13;16:1570095. doi: 10.3389/fphar.2025.1570095. eCollection 2025.

Abstract

Oliv () is a widely distributed plant with economic value, nutritional value, edible value and even medicinal value. In recent years, polysaccharides are considered to be one of the most important bioactive ingredients in . Modern pharmacological studies show that the crude extract of polysaccharides, their active monomer and ramifications have a wide range of pharmacological activities and experiments, which can be used to improve inflammation, regulate immunity, improve osteoporosis, and promote osseointegration, etc. Therefore, this review focuses on the induction and summary of the research at home and abroad in recent years, and summarizes the extraction and purification, modification methods, physicochemical properties, biological activities and potential mechanisms of polysaccharides, providing a theoretical basis for the in-depth study of polysaccharides and the development of related products.

摘要

橄榄是一种分布广泛的植物,具有经济价值、营养价值、食用价值甚至药用价值。近年来,多糖被认为是橄榄中最重要的生物活性成分之一。现代药理学研究表明,橄榄多糖的粗提物、其活性单体及衍生物在体内外实验中具有广泛的药理活性,可用于改善炎症、调节免疫、改善骨质疏松以及促进骨整合等。因此,本综述着重对近年来国内外的研究进行归纳总结,概括橄榄多糖的提取纯化、修饰方法、理化性质、生物学活性及潜在作用机制,为橄榄多糖的深入研究及相关产品开发提供理论依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e98/11966412/84c2e64df375/fphar-16-1570095-g001.jpg

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