Sogami M, Era S, Nagaoka S, Kuwata K, Kida K, Miura K, Inouye H, Suzuki E, Hayano S, Sawada S
Int J Pept Protein Res. 1985 Apr;25(4):398-402. doi: 10.1111/j.1399-3011.1985.tb02191.x.
Human mercaptalbumin (HMA) and nonmercaptalbumin (HNA) could be separated by high-performance liquid chromatography (HPLC) at neutral pH. Using HPLC, the present authors found the nonmercapt-mercapt conversion (HNA----HMA) during hemodialysis and the mercapt-nonmercapt conversion (HMA----HNA) after hemodialysis in chronic renal failure, indicating HMA as the covalent carrier protein for sulfur-containing amino acids.
人巯基白蛋白（HMA）和非巯基白蛋白（HNA）可在中性pH条件下通过高效液相色谱法（HPLC）分离。通过HPLC，作者发现慢性肾衰竭患者在血液透析期间存在非巯基-巯基转化（HNA→HMA），血液透析后存在巯基-非巯基转化（HMA→HNA），这表明HMA是含硫氨基酸的共价载体蛋白。
