非综合征性相邻/碰撞性脑膜瘤背景下的并发胶质肿瘤：病例说明
Concurrent glial tumors in the setting of a nonsyndromic adjacent/colliding meningioma: illustrative cases.
作者信息
Pour-Rashidi Ahmad, Nahang Fada Hossein, Gookizadeh Peyman, Karimi Yarandi Kourosh, Amirjamshidi Abbas, Nilipour Yalda, Shirani Mohammad
机构信息
Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Department of Neurosurgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
J Neurosurg Case Lessons. 2025 Apr 7;9(14). doi: 10.3171/CASE24805.
BACKGROUND
Meningioma, a common and mostly benign intracranial and spinal tumor, can coexist with other malignant tumors. Such a scenario is very rare in patients with no history of radiation therapy or phakomatosis. In this study, the authors present three cases of concurrent/adjacent CNS tumors, review the literature on this topic, and highlight some genomic alterations in that regard.
OBSERVATIONS
The authors present three cases of patients who had coexistence of meningioma with other glial tumors in this study.
LESSONS
Coexistence/collision of intracranial and spinal meningiomas with another CNS pathology occurs anecdotally. This phenomenon does not necessarily preclude resection of both tumors in a single session, provided that a careful preoperative assessment of the surgical anatomy is undertaken. Conducting studies to evaluate the genomic structures of such cases and to explain why they occur in adjacency could be valuable in explaining this phenomenon. https://thejns.org/doi/10.3171/CASE24805.
背景
脑膜瘤是一种常见的、大多为良性的颅内和脊髓肿瘤，可与其他恶性肿瘤共存。这种情况在无放射治疗史或神经皮肤综合征的患者中非常罕见。在本研究中，作者报告了3例同时发生/相邻的中枢神经系统肿瘤病例，回顾了关于该主题的文献，并强调了这方面的一些基因组改变。
观察结果
作者在本研究中报告了3例脑膜瘤与其他神经胶质瘤共存的患者病例。
经验教训
颅内和脊髓脑膜瘤与另一种中枢神经系统病变共存/碰撞的情况偶有发生。只要在术前仔细评估手术解剖结构，这种现象不一定排除在一次手术中切除两种肿瘤。开展研究以评估此类病例的基因组结构并解释它们为何相邻发生，可能有助于解释这一现象。https://thejns.org/doi/10.3171/CASE24805
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