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利用SWAN队列数据对中年女性生育胎次、分娩方式与尿失禁之间的关联进行纵向分析。

Longitudinal analysis of the association between parity, mode of delivery and urinary incontinence in midlife using the SWAN cohort data.

作者信息

Stephenson Nikki L, Brenner Darren, Brennand Erin, Robert Magali, Prisnie Kassi, Metcalfe Amy

机构信息

Department of Obstetrics & Gynecology, University of Calgary, Calgary, AB, Canada.

Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada.

出版信息

Sci Rep. 2025 Apr 7;15(1):11896. doi: 10.1038/s41598-025-85603-0.

DOI:10.1038/s41598-025-85603-0
PMID:40195346
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11977187/
Abstract

Parity increases the risk of urinary incontinence, but this risk differs by mode of delivery. This study evaluated the association between mode of delivery and prevalence of urge, stress, and mixed urinary incontinence in middle age. The association between mode of delivery and urinary incontinence subtypes was examined using data from the SWAN cohort. Women who experienced vaginal, cesarean, or combination deliveries were compared against nulliparous women. Women who delivered vaginally had a significantly higher prevalence of all subtypes of incontinence compared to women who were nulliparous or delivered via other modes. No significant differences in urinary incontinence were observed when comparing women who birthed vaginally, via cesarean, or combination to nulliparous women. However, in comparison to those who delivered via cesarean, women who delivered vaginally have significantly increased odds of experiencing stress urinary incontinence, and those who delivered via combination have significantly increased odds of experiencing mixed urinary incontinence. Urge urinary incontinence appears to be driven by aging, not childbearing. Compared to cesarean, vaginal deliveries increase the odds of stress and mixed urinary incontinence during middle age. Delivering via a combination of vaginal and cesarean sections increases the odds of mixed urinary incontinence during middle age.

摘要

经产会增加尿失禁的风险,但这种风险因分娩方式而异。本研究评估了分娩方式与中年女性急迫性、压力性和混合性尿失禁患病率之间的关联。使用来自SWAN队列的数据检查了分娩方式与尿失禁亚型之间的关联。将经历过阴道分娩、剖宫产或联合分娩的女性与未生育女性进行比较。与未生育或通过其他方式分娩的女性相比,经阴道分娩的女性所有失禁亚型的患病率显著更高。比较经阴道分娩、剖宫产或联合分娩的女性与未生育女性时,未观察到尿失禁有显著差异。然而,与剖宫产分娩的女性相比,经阴道分娩的女性发生压力性尿失禁的几率显著增加,而采用联合分娩方式的女性发生混合性尿失禁的几率显著增加。急迫性尿失禁似乎是由衰老而非生育导致的。与剖宫产相比,阴道分娩会增加中年女性发生压力性和混合性尿失禁的几率。采用阴道分娩和剖宫产相结合的方式会增加中年女性发生混合性尿失禁的几率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad2c/11977187/a058ad7ff2d0/41598_2025_85603_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad2c/11977187/391e5735b217/41598_2025_85603_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad2c/11977187/a058ad7ff2d0/41598_2025_85603_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad2c/11977187/391e5735b217/41598_2025_85603_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad2c/11977187/a058ad7ff2d0/41598_2025_85603_Fig2_HTML.jpg

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Prevalence of Female Urinary Incontinence in the General Population According to Different Definitions and Study Designs.根据不同的定义和研究设计,普通人群中女性尿失禁的患病率。
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