Liu Jinmei, Gu Hongxia, Jia Rui, Li Shuzhen, Chen Zhimin, Zheng Aijuan, Chang Wenhuan, Liu Guohua
Key Laboratory for Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing, China.
Front Vet Sci. 2025 Mar 18;12:1554502. doi: 10.3389/fvets.2025.1554502. eCollection 2025.
species have attracted more and more attention as a potential antibiotic substitute for human health and animal production due to their remarkable antibacterial effects. However, the underlying mechanism is unclear. This experiment's goal was to investigate the impacts of lactic acid bacteria (LAB) on the growth performance, carcass characteristics, immune function of broiler chickens and their mechanism.
One hundred and eighty 1-day-old AA broilers were used and randomly allocated into 3 treatment groups with 6 replicates of 10 chickens per replicate. The 3 treatment groups were control group (CK), added group (LAB-E, 1.0 × 108 CFU/kg) for the first 7 days; added group (LAB-A, 1.0 × 108 CFU/kg) for the whole experimental period. Broilers had free access to water and feed.
The results showed that addition of L. acidophilus for the whole experimental period significantly decreased ADFI, FCR and the abdominal fat percentage of broilers ( < 0.05), tended to increase the levels of IgG in broiler serum ( = 0.093). The LAB-A group had higher HDL-C content and IL-2, IL-4 content, and lower level of LPS in broiler serum compared to the controls ( < 0.05).
In conclusion, improved feed efficiency and immune function of broilers by controlling nutrient metabolism and inflammation responses of broilers. can be used as a potential substitute for antibiotics in broiler production.
由于其显著的抗菌作用,[具体菌种]作为一种潜在的抗生素替代品,在人类健康和动物生产方面越来越受到关注。然而,其潜在机制尚不清楚。本实验的目的是研究乳酸菌(LAB)对肉鸡生长性能、胴体特性、免疫功能的影响及其机制。
选用180只1日龄的AA肉鸡,随机分为3个处理组,每组6个重复,每个重复10只鸡。3个处理组分别为对照组(CK);在第1至7天添加乳酸菌组(LAB-E,1.0×10⁸CFU/kg);在整个实验期添加乳酸菌组(LAB-A,1.0×10⁸CFU/kg)。肉鸡自由饮水和采食。
结果表明,在整个实验期添加嗜酸乳杆菌显著降低了肉鸡的平均日采食量(ADFI)、料重比(FCR)和腹脂率(P<0.05),肉鸡血清中IgG水平有升高趋势(P=0.093)。与对照组相比,LAB-A组肉鸡血清中高密度脂蛋白胆固醇(HDL-C)含量、白细胞介素-2(IL-2)和白细胞介素-4(IL-4)含量较高,脂多糖(LPS)水平较低(P<0.05)。
综上所述,[具体菌种]通过调控肉鸡的营养代谢和炎症反应,提高了肉鸡的饲料效率和免疫功能,可作为肉鸡生产中抗生素的潜在替代品。