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康复状况在严重精神疾病患者社会经济地位与生活质量关联中的中介作用。

The mediating role of rehabilitation status on the association between socioeconomic status and quality of life among individuals with severe mental illness.

作者信息

Zhu Jianwen, Fu Jie, Wang Yang, Dong Jiajia, Zhang Xia, Wang Sizhe, Wen Lu, Fan Hong

机构信息

School of Nursing, Nanjing Medical University, 101 Longmian Road, Nanjing, China.

School of Public Health, Nanjing Medical University, Nanjing, China.

出版信息

BMC Psychiatry. 2025 Apr 7;25(1):339. doi: 10.1186/s12888-025-06782-8.

Abstract

BACKGROUND

Individuals with severe mental illness (SMI) often experience lower socioeconomic status (SES) and rehabilitation status, leading to a poorer quality of life (QoL). This study aimed to explore whether rehabilitation status serves as a mediating factor in the relationship between SES and QoL in individuals with SMI.

METHODS

A total of 1,105 individuals with SMI from 23 community health centers in Nanjing were recruited through a random sampling method. The General Information Questionnaire, the Morning Side Rehabilitation Status Scale and the Medical Outcomes Study Short Form 36-item Survey were used for assessment. Latent class analysis was employed to categorize patients' SES based on five socioeconomic indicators. Spearman's rank correlation analysis was used to investigate the relationships between SES, rehabilitation status, and QoL. Path analysis was used to estimate the direct effect between SES on QoL and the indirect effect mediated by rehabilitation status.

RESULTS

The 1,105 patients were categorized into two groups based on their SES: low SES (796 patients, 72%) and high SES (309 patients, 28%). The findings revealed a negative correlation between SES and rehabilitation scores (r = -0.142, p < 0.001), whereas a positive correlation was observed between SES and QoL (r = 0.180, p < 0.001). Furthermore, a negative correlation was found between rehabilitation scores and QoL (r = -0.608, p < 0.001). The study also found that the relationship between SES and QoL was partially mediated by rehabilitation status, with a mediating effect value of 32%.

CONCLUSIONS

Individuals with SMI experience impaired QoL, which may be improved by addressing both SES and rehabilitation status.

摘要

背景

重度精神疾病(SMI)患者往往社会经济地位(SES)较低且康复状况较差,导致生活质量(QoL)较低。本研究旨在探讨康复状况是否在SMI患者的SES与QoL之间的关系中起中介作用。

方法

通过随机抽样方法,从南京23个社区卫生中心招募了1105名SMI患者。使用一般信息问卷、晨边康复状况量表和医学结果研究简短形式36项调查进行评估。采用潜在类别分析,根据五项社会经济指标对患者的SES进行分类。采用Spearman等级相关分析来研究SES、康复状况和QoL之间的关系。采用路径分析来估计SES对QoL的直接效应以及康复状况介导的间接效应。

结果

根据SES,1105名患者被分为两组:低SES组(796例患者,72%)和高SES组(309例患者,28%)。研究结果显示,SES与康复评分之间呈负相关(r = -0.142,p < 0.001),而SES与QoL之间呈正相关(r = 0.180,p < 0.001)。此外,康复评分与QoL之间呈负相关(r = -0.608,p < 0.001)。该研究还发现,SES与QoL之间的关系部分由康复状况介导,中介效应值为32%。

结论

SMI患者的生活质量受损,通过改善SES和康复状况可能会有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91aa/11974079/567807510a66/12888_2025_6782_Fig1_HTML.jpg

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