Maldonado-Pérez Ashlie, Campos Joyce, Murray Gisela, Estronza Samuel, Pastrana Emil A
Department of Neurosurgery, University of Puerto Rico, Medical Sciences Campus, San Juan, PRI.
Department of Neurosurgery, San Juan Bautista School of Medicine, Caguas, PRI.
Cureus. 2025 Mar 9;17(3):e80295. doi: 10.7759/cureus.80295. eCollection 2025 Mar.
White cord syndrome (WCS) is a rare but serious postoperative complication after spinal decompression surgery. Risk factors such as advanced age, ossification of the posterior longitudinal ligament (OPLL), and major surgery may have predisposed this patient to develop WCS. This report discusses a 72-year-old Hispanic male patient with cervical stenosis due to OPLL who underwent posterior cervical decompression and fusion. After laminectomy and decompression were done, neuromonitoring signals decreased significantly. Despite intraoperative interventions after neuromonitoring signals decreased (e.g., mean arterial pressure augmentation with vasopressors, intravenous steroid therapy), the patient experienced significant quadriparesis following surgery. On postoperative imaging, spinal cord edema and T2 hyperintensities were noted on cervical MRI, consistent with the descriptions of WCS. The patient's postoperative course was marked by significant complications such as respiratory distress, hemodynamic instability, and infection, which ultimately led to his demise. This case highlights the necessity of individual risk factor stratification prior to surgery, careful neuromonitoring, and prompt treatment to manage suspected WCS.
白脊髓综合征(WCS)是脊柱减压手术后一种罕见但严重的术后并发症。诸如高龄、后纵韧带骨化(OPLL)和大型手术等风险因素可能使该患者易患WCS。本报告讨论了一名72岁的西班牙裔男性患者,因OPLL导致颈椎管狭窄,接受了颈椎后路减压融合术。在进行椎板切除术和减压术后,神经监测信号显著下降。尽管在神经监测信号下降后进行了术中干预(如使用血管升压药提高平均动脉压、静脉注射类固醇治疗),但患者术后仍出现明显的四肢瘫。术后影像学检查显示,颈椎MRI上可见脊髓水肿和T2高信号,与WCS的描述相符。患者术后病程出现了呼吸窘迫、血流动力学不稳定和感染等严重并发症,最终导致死亡。本病例强调了术前进行个体风险因素分层、仔细的神经监测以及对疑似WCS进行及时治疗的必要性。