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一例因感染性全髋关节置换翻修术导致草酸盐肾病的病例报告

A Revision of an Infected Total Hip Arthroplasty leading to Oxalate Nephropathy: A Case Report.

作者信息

Mouselimis Dimitrios, Özcan Fedai, Wiech Thorsten, Lüring Christian

机构信息

Department of Orthopaedic Surgery, Klinikum Dortmund, Witten/Herdecke University, Dortmund, Germany.

Department of Nephrology, Klinikum Dortmund, Witten/Herdecke University, Germany.

出版信息

J Orthop Case Rep. 2025 Apr;15(4):90-94. doi: 10.13107/jocr.2025.v15.i04.5456.

Abstract

INTRODUCTION

Although one of the most successful orthopedic procedures, total hip arthroplasty (THA) conveys a not negligible risk for complications.

CASE REPORT

A 72-year-old patient after a THA received an operative revision 2 times due to persistent hematoma and early periprothetic infection. Post-operative renal failure requiring hemodialysis has been caused by a histologically confirmed oxalate nephropathy (ON). Post-operative antibiotic treatment altering the gut microbiome has been assumed as the most likely cause of ON. It is the first presented case of ON as a post-operative complication after a hip arthroplasty revising operation.

CONCLUSION

Acute post-operative renal injury conveys significant danger for the patients. An interdisciplinary approach is needed as many cases require complex diagnostic and therapeutical procedures offered by experts on the field.

摘要

引言

尽管全髋关节置换术(THA)是最成功的骨科手术之一,但它仍存在不可忽视的并发症风险。

病例报告

一名72岁患者在接受全髋关节置换术后,因持续血肿和早期假体周围感染接受了2次手术翻修。组织学确诊的草酸盐肾病(ON)导致术后肾衰竭,需要进行血液透析。术后抗生素治疗改变肠道微生物群被认为是草酸盐肾病最可能的原因。这是首次报道的全髋关节置换翻修手术后草酸盐肾病作为术后并发症的病例。

结论

急性术后肾损伤对患者构成重大危险。由于许多病例需要该领域专家提供的复杂诊断和治疗程序,因此需要采取多学科方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6ce/11981481/21e6542c5a68/JOCR-15-90-g001.jpg

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