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久坐行为对心脏代谢健康的潜在危害在高度活跃的成年人中会减轻:一项成分数据分析。

The potential harms of sedentary behaviour on cardiometabolic health are mitigated in highly active adults: a compositional data analysis.

作者信息

Franssen Wouter M A, Jermei Jarne, Savelberg Hans H C M, Eijnde Bert O

机构信息

REVAL-Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, 3500, Hasselt, Belgium.

SMRC-Sports Medicine Research Center, BIOMED-Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, Agoralaan, Building A, Diepenbeek, 3500, Hasselt, Belgium.

出版信息

J Act Sedentary Sleep Behav. 2023 Mar 2;2(1):6. doi: 10.1186/s44167-023-00015-7.

Abstract

BACKGROUND

Insufficient physical activity and sedentary behaviour (SB) are important factors that determine cardiometabolic health and the development of non-communicable diseases. The aim of this study was to investigate the modifying effects of moderate-to-vigorous physical activity (MVPA) on the association between SB and cardiometabolic health within highly active adults.

METHODS

In a cross-sectional design, 61 (male/female: 41/20) highly trained adults (age: 33.6 ± 10.7 years; BMI: 22.4 ± 2.3 kg/m) performed a maximal cardiopulmonary exercise test from which indicators for peak performance were determined. Physical activity and SB were assessed using the activPAL3™ accelerometer. In addition, anthropometrics, blood pressure, plasma lipids and insulin sensitivity were assessed. These cross-sectional associations between a daily movement behaviour composition and cardiometabolic health parameters were investigated using a compositional data analysis approach.

RESULTS

Participants spent 600 ± 86 min/day in SB and engaged in almost 1.5 h per day of MVPA. No association was found between SB and cardiometabolic health related variables, whereas MVPA (β = 8.07 ± 2.18; r = 0.544; p < 0.001) was only significantly associated with oxygen uptake, relative to all other remaining behaviours.

CONCLUSION

No associations were found between the time spent in SB and cardiometabolic health related outcomes, possibly due to the high amount of time spent in MVPA within highly active adults.

TRIAL REGISTRATION

The present study was registered on the 14th of January 2022 at clinicaltrials.gov (NCT04711928).

摘要

背景

身体活动不足和久坐行为是决定心血管代谢健康和非传染性疾病发展的重要因素。本研究的目的是调查中等到剧烈身体活动(MVPA)对高活动水平成年人久坐行为与心血管代谢健康之间关联的调节作用。

方法

采用横断面设计,61名(男性/女性:41/20)训练有素的成年人(年龄:33.6±10.7岁;体重指数:22.4±2.3kg/m²)进行了最大心肺运动试验,从中确定了峰值表现指标。使用activPAL3™加速度计评估身体活动和久坐行为。此外,还评估了人体测量学、血压、血脂和胰岛素敏感性。使用成分数据分析方法研究了日常运动行为组成与心血管代谢健康参数之间的这些横断面关联。

结果

参与者每天久坐600±86分钟,每天进行近1.5小时的MVPA。未发现久坐行为与心血管代谢健康相关变量之间存在关联,而相对于所有其他剩余行为,MVPA(β=8.07±2.18;r=0.544;p<0.001)仅与摄氧量显著相关。

结论

未发现久坐行为时间与心血管代谢健康相关结果之间存在关联,这可能是由于高活动水平成年人在MVPA上花费的时间较多。

试验注册

本研究于2022年1月14日在clinicaltrials.gov(NCT04711928)注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6277/11960216/bb61164dbd9a/44167_2023_15_Fig1_HTML.jpg

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