McCarthy Andrew A, Basu Shibom, Bernaudat Florent, Blakeley Matthew P, Bowler Matthew W, Carpentier Philippe, Effantin Gregory, Engilberge Sylvain, Flot David, Gabel Frank, Gajdos Lukas, Kamps Jos J A G, Kandiah Eaazhisai, Linares Romain, Martel Anne, Melnikov Igor, Mossou Estelle, Mueller-Dieckmann Christoph, Nanao Max, Nurizzo Didier, Pernot Petra, Popov Alexander, Royant Antoine, de Sanctis Daniele, Schoehn Guy, Talon Romain, Tully Mark D, Soler-Lopez Montserrat
European Molecular Biology Laboratory (EMBL), Grenoble, France.
European Synchrotron Radiation Facility (ESRF), Grenoble, France.
J Synchrotron Radiat. 2025 May 1;32(Pt 3):577-594. doi: 10.1107/S1600577525002012. Epub 2025 Apr 14.
The European Photon and Neutron campus in Grenoble is a unique site, encompassing the European Synchrotron Radiation Facility Extremely Brilliant Source, the Institut Laue-Langevin, the European Molecular Biology Laboratory and the Institut de Biologie Structurale. Here, we present an overview of the structural biology beamlines, instruments and support facilities available on the EPN campus. These include advanced macromolecular crystallography using neutrons or X-rays, small-angle X-ray or neutron scattering, cryogenic electron microscopy, and spectroscopy. These highly complementary experimental approaches support cutting-edge research for integrated structural biology in our large user community. This article emphasizes our significant contributions to the field, outlines current advancements made and provides insights into our future prospects, offering readers a comprehensive understanding of the EPN campus's role in advancing integrated structural biology research.
位于格勒诺布尔的欧洲光子与中子研究园区是一个独特的场所，涵盖了欧洲同步辐射装置极亮光源、劳厄-朗之万研究所、欧洲分子生物学实验室和结构生物学研究所。在此，我们概述了欧洲光子与中子研究园区现有的结构生物学光束线、仪器和支持设施。这些包括使用中子或X射线的先进大分子晶体学、小角X射线或中子散射、低温电子显微镜和光谱学。这些高度互补的实验方法支持了我们广大用户群体中前沿的综合结构生物学研究。本文强调了我们在该领域的重大贡献，概述了当前取得的进展，并对我们的未来前景进行了展望，使读者全面了解欧洲光子与中子研究园区在推进综合结构生物学研究中的作用。
