生物大分子的辐射损伤∗
Radiation damage to biological macromolecules∗.
作者信息
Garman Elspeth F, Weik Martin
机构信息
Department of Biochemistry, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford, OX1 3QU, UK.
Univ. Grenoble Alpes, CEA, CNRS, Institut de Biologie Structurale, F-38044 Grenoble, France.
出版信息
Curr Opin Struct Biol. 2023 Oct;82:102662. doi: 10.1016/j.sbi.2023.102662. Epub 2023 Aug 11.
In this review, we describe recent research developments into radiation damage effects in macromolecular X-ray crystallography observed at synchrotrons and X-ray free electron lasers. Radiation damage in small molecule X-ray crystallography, small angle X-ray scattering experiments, microelectron diffraction, and single particle cryo-electron microscopy is briefly covered.
在本综述中，我们描述了在同步加速器和X射线自由电子激光上观察到的大分子X射线晶体学中辐射损伤效应的最新研究进展。小分子X射线晶体学、小角X射线散射实验、微电子衍射和单颗粒冷冻电子显微镜中的辐射损伤也将简要介绍。
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