Gu Dongqing, Ou Shan, Liu Guodong
Department of Obstetrics and Gynecology, Chongqing Health Center for Women and Children (Women and Children's Hospital of Chongqing Medical University), Chongqing, China.
Department of Anesthesiology, First People's Hospital of Chengdu, Chengdu, China.
Prev Med Rep. 2025 Mar 27;53:103051. doi: 10.1016/j.pmedr.2025.103051. eCollection 2025 May.
To systematically estimate the burden of road injuries and associated risk factors. Data on incidence, deaths, and disability-adjusted life years (DALYs) with 95 % uncertainty intervals, by age, sex, sociodemographic index, region, and country, from 1990 to 2021, were obtained from the Global Burden of Disease Study 2021. In addition, we obtained the numbers of DALYs and deaths attributed to risk factors. Joinpoint regression analysis was used to calculate the average annual percentage changes and 95 % confidence intervals (CIs). In 2021, the incident cases of road injuries were 50.3 million (95 % uncertainty interval: 45.7 to 55.2) globally, with an age-standardized incidence (ASIR) of 627.8 per 100,000 population (95 % uncertainty interval: 570.6 to 688.1). From 1990 to 2021, the ASIR was decreased by an average of 1.52 (95 % CI: -1.55 to -1.49) per year. Substantial heterogeneity was observed, particularly among youth aged 25-29 years, males, and high-income North America. Road injuries caused 65.1 million (95 % uncertainty interval: 60.7 to 69.9) DALYs and 1195.7 thousand (95 % uncertainty interval: 1118.2 to 1275.7) deaths in 2021. High burden was observed in older people, males, Central Sub-Saharan Africa, and countries with low income. Motor vehicles (36.6 %) and pedestrians (36.8 %) were the main causes of death. In particular, 72.2 % of road injuries were attributable to occupational injuries for males, while 57.7 % were attributable to low bone mineral density for females. This study suggests a decreasing global burden of road injuries. Nonetheless, road safety remains a significant global public health issue.
系统评估道路伤害负担及相关风险因素。从《2021年全球疾病负担研究》中获取了1990年至2021年按年龄、性别、社会人口指数、地区和国家划分的发病率、死亡人数以及残疾调整生命年（DALY）数据，并带有95%的不确定性区间。此外，我们还获取了归因于风险因素的DALY和死亡人数。采用Joinpoint回归分析来计算年均百分比变化和95%置信区间（CI）。2021年，全球道路伤害事件病例数为5030万（95%不确定性区间：4570万至5520万），年龄标准化发病率（ASIR）为每10万人627.8例（95%不确定性区间：570.6至688.1）。1990年至2021年期间，ASIR平均每年下降1.52（95% CI：-1.55至-1.49）。观察到存在显著的异质性，尤其是在25至29岁的年轻人、男性以及高收入的北美洲人群中。2021年，道路伤害导致6510万（95%不确定性区间：6070万至6990万）DALY以及119.57万（95%不确定性区间：111.82万至127.57万）人死亡。在老年人、男性、撒哈拉以南非洲中部地区以及低收入国家中观察到高负担情况。机动车（36.6%）和行人（36.8%）是主要死亡原因。特别是，72.2%的道路伤害归因于男性的职业伤害，而57.7%归因于女性的低骨矿物质密度。本研究表明全球道路伤害负担在下降。尽管如此，道路安全仍然是一个重大的全球公共卫生问题。
