一个由分子生物学引领的免疫学发现时代。
An era of immunological discoveries heralded by molecular biology.
作者信息
Kenter Amy, Singh Harinder
机构信息
Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL, USA.
Center for Systems Immunology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA, USA.
出版信息
Trends Immunol. 2025 May;46(5):364-371. doi: 10.1016/j.it.2025.03.003. Epub 2025 Apr 15.
The Molecular Mechanisms of Immune Cell Development and Function (MMICDF) meeting sponsored by the Federation of American Societies of Experimental Biology (FASEB) occupies a special niche because of its focus on the molecular mechanisms that underpin immunological processes. This biennial meeting with small groupings of participants and interactive nature has provided a forum for intense, informative, and influential scientific discussions. The meeting is unique for its focus on molecular mechanisms that control the exceptional processes of DNA recombination, somatic hypermutation (SHM), and gene expression during immune cell development, activation, and differentiation. The organizers of the foundational meeting reflect on the coalescence of scientific advances that catalyzed its origin, review meeting highlights to celebrate its 20th anniversary, and project into the future.
由美国实验生物学学会联合会（FASEB）主办的免疫细胞发育与功能分子机制（MMICDF）会议因其专注于支撑免疫过程的分子机制而占据特殊地位。这个每两年举办一次、参与者分组规模小且具有互动性的会议，为深入、信息丰富且有影响力的科学讨论提供了一个平台。该会议的独特之处在于其专注于控制免疫细胞发育、激活和分化过程中DNA重组、体细胞超突变（SHM）以及基因表达等特殊过程的分子机制。此次基础会议的组织者回顾了促成其诞生的科学进展的融合，回顾会议亮点以庆祝其成立20周年，并展望未来。
Zotero 插件