Hoogervorst Lotje, Nelissen Rob G H H, Van Steenbergen Liza, Pedersen Alma B, Kristiansen Eskild Bendix, Lindberg-Larsen Martin, Torre Marina, Ciminello Enrico, Valentini Riccardo, Grimberg Alexander W, Wu Yinan, Marang-van de Mheen Perla J
Department of Orthopaedics, Leiden University Medical Center, Leiden, the Netherlands.
Dutch Arthroplasty Register (LROI), 's- Hertogenbosch, the Netherlands.
Acta Orthop. 2025 Apr 17;96:339-347. doi: 10.2340/17453674.2025.43476.
Pooling data on the performance of total knee (TK) implants across registries is only possible if the same TK implant is used across multiple registries and if used in patients with similar characteristics. We assessed to what extent specific TK implants: (i) are used across multiple registries or only in a single registry; and (ii) differ in patient characteristics between registries.
All primary TK implants implanted between January 2020 and December 2021 in the Danish, Dutch, German, and Italian registries were included. We determined the number of registries using a specific TK implant (based on combined femoral-tibial component brand name and fixation/congruency/mobile bearing insert/patella usage). Patient characteristics (age/body mass index [BMI]/sex/diagnosis osteoarthritis) were compared across registries for TK implants used in ≥ 2 registries ≥ 100 times.
813 different TK implants (577,351 procedures) were used across the 4 registries, of which 53 TK implants (7%) were used in 1 registry (8,000 procedures). 760 different TK implants (569,351 procedures; 99%) were used in ≥ 2 registries of which 47 different TK implants (393,954 procedures; 68%) were used in ≥ 2 registries and ≥ 100 times. Statistically and clinically significant differences in age for the same TK implant across registries were observed for 29 TK implants (62%) and 3 TK implants (6%), respectively; for other characteristics these were for BMI 30 (64%) and 0 (0%) TK implants; for male proportion 23 (49%) and 17 (36%) TK implants; and for diagnosis of osteoarthritis 42 (89%) and 34 (72%) TK implants, respectively.
Most specific TK implants and TK procedures were used across multiple registries, but they were often used in patients with different characteristics. This has an impact on comparing implant performances between registries.
只有在多个登记处使用相同的全膝关节（TK）植入物，且用于特征相似的患者时，才有可能汇总各登记处TK植入物的性能数据。我们评估了特定TK植入物在以下方面的程度：（i）在多个登记处使用还是仅在单个登记处使用；（ii）各登记处患者特征的差异。
纳入2020年1月至2021年12月在丹麦、荷兰、德国和意大利登记处植入的所有初次TK植入物。我们根据特定的TK植入物（基于股骨 - 胫骨组件组合品牌名称以及固定方式/匹配度/活动轴承插入物/髌骨使用情况）确定使用该植入物的登记处数量。对在≥2个登记处使用≥100次的TK植入物，比较各登记处的患者特征（年龄/体重指数[BMI]/性别/骨关节炎诊断）。
4个登记处共使用了813种不同的TK植入物（577,351例手术），其中53种TK植入物（7%）仅在1个登记处使用（8,000例手术）。760种不同的TK植入物（569,351例手术；99%）在≥2个登记处使用，其中47种不同的TK植入物（393,954例手术；68%）在≥2个登记处且使用次数≥100次。对于相同的TK植入物，各登记处在年龄方面，分别观察到29种（62%）和3种（6%）存在统计学和临床显著差异；对于其他特征，BMI方面分别有30种（64%）和0种（0%）存在差异；男性比例方面分别有23种（49%）和17种（36%）存在差异；骨关节炎诊断方面分别有42种（89%）和34种（72%）存在差异。
大多数特定的TK植入物和TK手术在多个登记处使用，但它们通常用于特征不同的患者。这对比较各登记处植入物的性能有影响。
