Kawamura Akiyuki, Mori Ryusaburo, Tanaka Koji, Wakatsuki Yu, Fujita Kyoko, Nakashizuka Hiroyuki
Division of Ophthalmology, Department of Visual Science, Nihon University Hospital, Nihon University School of Medicine, 1-6, Kanda-Surugadai Chiyodaku, Tokyo, 101-8309, Japan.
Aichi Medical University, Nagakute, Japan.
Jpn J Ophthalmol. 2025 Apr 18. doi: 10.1007/s10384-025-01188-1.
Asymmetric dilated vortex veins (ADVV) extending continuously to the vortex ampullae seen on Indocyanine green angiography (ICGA) findings, are thought to indicate choroidal venous congestion in central serous chorioretinopathy (CSC). In addition, the sclera is thickened compared to normal eyes, suggesting that obstruction of the scleral passage is the pathophysiological mechanism of CSC. The purpose of this study was to examine the choroidal circulation in and around the vortex vein ampulla.
Single-center retrospective study.
The subjects were 23 CSC eyes with macular central serous detachment (SRD) undergoing wide-field ICGA with Spectralis. Choroidal circulation time was defined as the time from the onset of filling in the choroidal artery to the first appearance of dye in the vortex vein ampulla. The choroidal circulation time in the superior and inferior vortex veins were measured separately. The relationship between the ADVV and the choroidal circulation time was investigated.
The mean choroidal circulation time was 4.44 seconds for the superior temporal side and 4.33 seconds for the inferior temporal side, with no significant difference (p=0.494). The mean choroidal circulation time was 3.89 seconds on the ADVV side and 4.88 seconds on the non-ADVV side, with a shorter mean circulation time on the ADVV side (p=0.00005). In 21 of 23 eyes, there was a time difference in the filling of the choroidal veins entering the vortex vein ampulla.
On the side of the ADVV, no obstruction to the passage of the sclera is thought to have occurred.
吲哚菁绿血管造影（ICGA）检查发现不对称扩张的涡静脉（ADVV）持续延伸至涡静脉壶腹，被认为提示中心性浆液性脉络膜视网膜病变（CSC）存在脉络膜静脉充血。此外，与正常眼相比巩膜增厚，提示巩膜通道阻塞是CSC的病理生理机制。本研究旨在检查涡静脉壶腹及其周围的脉络膜循环。
单中心回顾性研究。
研究对象为23例患有黄斑中心性浆液性脱离（SRD）的CSC患者，使用海德堡Spectralis进行超广角ICGA检查。脉络膜循环时间定义为从脉络膜动脉开始充盈到染料首次出现在涡静脉壶腹的时间。分别测量上下涡静脉的脉络膜循环时间。研究ADVV与脉络膜循环时间之间的关系。
颞上侧平均脉络膜循环时间为4.44秒，颞下侧为4.33秒，无显著差异（p = 0.494）。ADVV侧平均脉络膜循环时间为3.89秒，非ADVV侧为4.88秒，ADVV侧平均循环时间较短（p = 0.00005）。23只眼中有21只眼，进入涡静脉壶腹的脉络膜静脉充盈存在时间差异。
在ADVV侧，未发生巩膜通道阻塞。
