Shahzad Tariq, Mazhar Tehseen, Saqib Sheikh Muhammad, Ouahada Khmaies
Department of Electrical and Electronic Engineering Science, University of Johannesburg, Johannesburg, 2006, South Africa.
School of Computer Science, National College of Business Administration and Economics, Lahore 54000, Pakistan.
Sci Rep. 2025 Apr 18;15(1):13501. doi: 10.1038/s41598-025-98523-w.
Breast cancer is a leading killer and has been deepened by COVID-19, which affected diagnosis and treatment services. The absence of a rapid, efficient, accurate diagnostic tool remains a pressing issue for this severe disease. Thus, it is still possible to encounter issues concerning diagnostic accuracy and utilization of errors in the sphere of machine learning, deep learning, and transfer learning models. This paper presents a new model combining EfficientNetB0 and ResNet50 to improve the classification of breast histopathology images into IDC and non-IDC classes. The implementation steps, it include resizing all the images to be of a standard size of 128*128 pixels and then performing normalization to enhance the learning model. EfficientNetB0 is selected for its efficient yet effective performance while ResNet50 employs deep residual connections to overcome the vanishing gradient problem. The proposed model that incorporates some of the characteristics from both architectures turns out to be very resilient and accurate in classification. The model demonstrates superior performance with an accuracy of 94%, a Mean Absolute Error (MAE) of 0.0628, and a Matthews Correlation Coefficient (MCC) of 0.8690. These results outperform previous baselines and show that the model performs well in achieving a good trade-off between precision and recall. The comparison with the related works demonstrates the superiority of the proposed ensemble approach in terms of accuracy and complexity, which makes it efficient for practical breast cancer diagnosis and screening.
乳腺癌是主要杀手,且受新冠疫情影响诊断和治疗服务,情况愈发严重。对于这种严重疾病而言,缺乏快速、高效、准确的诊断工具仍是紧迫问题。因此,在机器学习、深度学习和迁移学习模型领域,仍可能遇到诊断准确性和错误利用方面的问题。本文提出一种结合EfficientNetB0和ResNet50的新模型,以改善乳腺组织病理学图像分类为浸润性导管癌(IDC)和非IDC类别的效果。实施步骤包括将所有图像调整为标准大小128*128像素,然后进行归一化以增强学习模型。选择EfficientNetB0是因其高效且有效,而ResNet50采用深度残差连接来克服梯度消失问题。结合两种架构部分特征的所提模型在分类中表现出很强的适应性和准确性。该模型表现卓越,准确率达94%,平均绝对误差(MAE)为0.0628,马修斯相关系数(MCC)为0.8690。这些结果优于先前的基线,表明该模型在实现精度和召回率之间的良好平衡方面表现出色。与相关工作的比较证明了所提集成方法在准确性和复杂性方面的优越性,这使其在实际乳腺癌诊断和筛查中效率很高。