Saaidi Rahal, Tayalati Yahya, Elfatimy Abdelouahed
School of Applied and Engineering Physics, Mohammed VI Polytechnic University, Lot 660, Hay Moulay Rachid, 43150, Ben Guerir, Morocco.
Faculty of Sciences, Mohammed V University in Rabat, Avenue des Nations Unies, Rabat, Morocco.
Sci Rep. 2025 Apr 22;15(1):13847. doi: 10.1038/s41598-025-95670-y.
Positron Emission Tomography (PET) is a valuable tool for plant imaging, but its accuracy can be compromised by positron range effects. This study improves PET accuracy using the GATE Monte Carlo simulation tool to estimate and correct these effects. The GATE model was validated for the Siemens Biograph Vision system using the NEMA NU 2-2018 protocol, showing alignment with experimental data. Deviations were within 9% for sensitivity and 3% for peak Noise Equivalent Count Rate (NECR). Different isotopes (F, C, O, and P) and plant phantom properties were analyzed for their impact on reconstructed images. A sixfold enhancement was observed for O and a threefold improvement for C when a magnetic field was applied to the plant phantom. Our findings suggest that integrating PET with magnetic resonance imaging can help address Positron range effects in plant imaging. This study provides valuable insights into PET imaging and offers refined methodologies for clinical and plant-centric research. Our research validates the use of GATE Monte Carlo simulation for Biograph Vision and advances our understanding of Positron range phenomena and potential mitigation strategies for precise PET Plant imaging.
正电子发射断层扫描(PET)是植物成像的一种有价值的工具,但其准确性可能会受到正电子射程效应的影响。本研究使用GATE蒙特卡罗模拟工具来估计和校正这些效应,从而提高PET的准确性。使用NEMA NU 2-2018协议对西门子Biograph Vision系统的GATE模型进行了验证,结果表明该模型与实验数据相符。灵敏度偏差在9%以内,峰值噪声等效计数率(NECR)偏差在3%以内。分析了不同同位素(F、C、O和P)以及植物模型属性对重建图像的影响。当对植物模型施加磁场时,观察到O的增强倍数为6倍,C的改善倍数为3倍。我们的研究结果表明,将PET与磁共振成像相结合有助于解决植物成像中的正电子射程效应。本研究为PET成像提供了有价值的见解,并为临床和以植物为中心的研究提供了完善的方法。我们的研究验证了GATE蒙特卡罗模拟在Biograph Vision中的应用,并推进了我们对正电子射程现象以及精确PET植物成像潜在缓解策略的理解。