Zeng Nannan, Liu Haiyang, Wang Jian, Jiang Lizhu
School of TCM and Pharmacology Health and Early Childhood Care, Ningbo College of Health Sciences, Ningbo, China.
Department of Physical Education, Ningbo University of Technology, Ningbo, China.
Front Physiol. 2025 Apr 10;16:1558008. doi: 10.3389/fphys.2025.1558008. eCollection 2025.
This study aims to comprehensively explore the effects of blood flow restriction (BFR) training on the post-activation potentiation (PAP) and the rating of perceived exertion (RPE) through meta-analysis, so as to provide a scientific basis for athletes' physical fitness training.
The PubMed, CNKI, Web of Science and EBSCO databases were searched to look for randomized controlled trials (RCTs) on the effects of BFRT on post-activation potentiation (PAP) and the rating of perceived exertion (RPE). The Cochrane risk of bias tool was used to screen the literature. With the help of Revman 5.4 and Stata 17.0 software, the literature quality assessment and statistical analysis were completed. Meanwhile, sensitivity analysis and funnel plots were utilized to examine the stability of the results and the publication bias.
A total of 31 related studies were included, among which 22 studies focused on the relationship between BFR training and PAP, covering 347 participants. Meta-analysis showed that BFRT could significantly affect PAP [ = 0.49, 95% CI (0.20, 0.77), = 0.0008]. When the testing method was Squat Jump [ = 1.35, 95% CI (0.40, 2.30), < 0.0005], the exercise intensity was 40%-70% 1RM [ = 1.21, 95% CI (0.69, 1.73), < 0.0001], and the compression intensity was ≤50% AOP [ = 0.77, 95% CI (0.24, 1.30), = 0.05], the effects on PAP reached the maximum, respectively, and were statistically significant. In terms of the impact of BFR training on RPE, 18 studies with 238 subjects were included. BFR training could significantly increase the RPE of the subjects [ = 1.21, 95% CI (0.69, 1.73), < 0.0001]. When the exercise mode was Knee flexion [ = 0.65, 95% CI (0.18, 1.11), = 0.0006], the exercise intensity was Mixed oxygen Training [ = 1.03, 95% CI (0.50, 1.56), = 0.0001], and the compressive strength was ≥60% AOP [ = 0.75, 95% CI (0.02, 1.48), = 0.05], a more significant effect size was presented.
Blood flow restriction training can induce the occurrence of post-activation potentiation (PAP). BFR exercises with 40%-70% 1RM and ≤50% AOP are more likely to stimulate PAP. Meanwhile, BFR training will significantly affect the rating of perceived exertion (RPE). BFR training under mixed oxygen training and with a compressive strength of ≥60% AOP has a stronger perception of fatigue. http://inplasy.com, identifier INPLASY202430008.
本研究旨在通过荟萃分析全面探讨血流限制（BFR）训练对激活后增强（PAP）和主观用力感觉评分（RPE）的影响，为运动员体能训练提供科学依据。
检索PubMed、CNKI、Web of Science和EBSCO数据库，查找关于BFR训练对激活后增强（PAP）和主观用力感觉评分（RPE）影响的随机对照试验（RCT）。使用Cochrane偏倚风险工具筛选文献。借助Revman 5.4和Stata 17.0软件完成文献质量评估和统计分析。同时，利用敏感性分析和漏斗图检验结果的稳定性和发表偏倚。
共纳入31项相关研究，其中22项研究聚焦于BFR训练与PAP的关系，涉及347名参与者。荟萃分析表明，BFR训练可显著影响PAP[效应量 = 0.49，95%置信区间（0.20，0.77），P = 0.0008]。当测试方法为深蹲跳[效应量 = 1.35，95%置信区间（0.40，2.30），P < 0.0005]、运动强度为40%-70% 1RM[效应量 = 1.21，95%置信区间（0.69，1.73），P < 0.0001]、压迫强度≤50% AOP[效应量 = 0.77，95%置信区间（0.24，1.30），P = 0.05]时，对PAP的影响分别达到最大值，且具有统计学意义。在BFR训练对RPE的影响方面，纳入18项研究，涉及238名受试者。BFR训练可显著提高受试者的RPE[效应量 = 1.21，95%置信区间（0.69，1.73），P < 0.0001]。当运动模式为屈膝[效应量 = 0.65，95%置信区间（0.18，1.11），P = 0.0006]、运动强度为混合氧训练[效应量 = 1.03，95%置信区间（0.50，1.56），P = 0.0001]、压迫强度≥60% AOP[效应量 = 0.75，95%置信区间（0.02，1.48），P = 0.05]时，呈现出更显著的效应量。
血流限制训练可诱导激活后增强（PAP）的发生。采用40%-70% 1RM且压迫强度≤50% AOP的BFR运动更易刺激PAP。同时，BFR训练将显著影响主观用力感觉评分（RPE）。在混合氧训练且压迫强度≥60% AOP的条件下进行BFR训练，疲劳感更强。http://inplasy.com，标识符INPLASY202430008 。
