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基于巴巴科配方凝胶的化学机械去龋组织学评价

Histological Evaluation of Chemo Mechanical Caries Removal with a Babaco-Based Formulation Gel.

作者信息

Pariona-Minaya María Del Carmen, Berrezueta-Pérez Melissa, Cabezas-Bernhardt Gerson, Villavicencio-Caparo Ebingen

机构信息

Faculty of Dentistry, University Peruana Cayetano Heredia, Lima 15102, Peru.

Health and Wellness Department, Faculty of Dentistry, Catholic University of Cuenca, Cuenca 010107, Ecuador.

出版信息

Gels. 2025 Apr 1;11(4):257. doi: 10.3390/gels11040257.

Abstract

The study investigated the effectiveness of a babaco-based gel derived from an endemic Ecuadorian fruit for chemomechanical caries removal compared to the conventional non-rotary mechanical method. Babaco contains proteolytic enzymes that soften decayed dental tissue, making it a potential alternative for caries treatment. An ex vivo experimental study was carried out using sixty extracted human teeth, each divided into two sections: one treated with babaco gel and the other with a spoon excavator. Four extraction methods (maceration, distillation, Soxhlet, and percolation) were used to prepare the gel. After rehydration and submersion in nitric acid, an oral pathologist evaluated the efficacy of caries removal. Results showed a 78% success rate for the babaco-treated sections, significantly higher than the 14% success rate for the conventional method. The distillation-extracted gel subgroup performed best at < 0.01 Fisher Chi. The study concluded that babaco gel is more effective for caries removal than traditional methods, highlighting its potential as a chemical-mechanical alternative.

摘要

该研究调查了一种源自厄瓜多尔本土水果的巴巴科凝胶与传统非旋转机械方法相比,在化学机械性龋洞去除方面的有效性。巴巴科含有蛋白水解酶,可软化龋坏的牙齿组织,使其成为龋齿治疗的一种潜在替代方法。使用60颗拔除的人牙进行了一项体外实验研究,每颗牙齿分为两部分:一部分用巴巴科凝胶处理,另一部分用匙形挖器处理。采用四种提取方法(浸渍法、蒸馏法、索氏提取法和渗漉法)制备凝胶。在再水化并浸入硝酸后,一名口腔病理学家评估了龋洞去除的效果。结果显示,用巴巴科处理的部分成功率为78%,显著高于传统方法的14%成功率。蒸馏提取凝胶亚组在Fisher卡方检验中表现最佳(P<0.01)。该研究得出结论,巴巴科凝胶在去除龋坏方面比传统方法更有效,突出了其作为化学机械替代方法的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a181/12027084/bfae07fd643e/gels-11-00257-g001.jpg

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