Dhobi Saddam Husain, Subedi Pramod, Neupane Bishnu, Mulmi Dikshya, Mulmi Deependra Das
Physical Science Laboratory, Nepal Academy of Science and Technology, Lalitpur, 44700, Nepal.
Department of General Practice and Emergency Medicine, KIST Medical College and Teaching Hospital, Lalitpur, 44705, Nepal.
Sci Rep. 2025 Apr 25;15(1):14541. doi: 10.1038/s41598-025-92953-2.
Fenugreek water, with its natural brilliance and dual magic, shines as a green catalyst for health and beauty. From managing diabetes to rejuvenating skin, discover the science behind this age-old remedy turned modern marvel that shows more detail study on fenugreek water. This study investigates the structural and optical properties of fenugreek water, examining its interactions with sugar solutions, anti-diabetes medications (Diapride M2 Forte), and sunscreen cream (shadow SPF50 + cream) over a period of 3 days. X-ray diffraction (XRD) of soaking fenugreek seed powder in water shows the peak intensity increased significantly from day 1 to day 3 because gel-like mucilage forms. The fenugreek seed powder exhibited broader peaks compared to the more crystalline diabetes medications, reflecting a less organized polysaccharide structure. The optical studies of fenugreek water mixed with sugar solutions (125 mg/dl, 155 mg/dl, and 185 mg/dl) showed that absorbance decreased as sugar concentration increased but increased with higher volumes of fenugreek water, revealing colloidal interactions. On day 1, the absorbance peak was around 250 nm, but days 2 and 3 introduced additional peaks at 350 nm, indicating evolving colloidal particle sizes. When mixed with anti-diabetes drugs, fenugreek water exhibited increased absorbance on day 3, suggesting enhanced interaction. Additionally, fenugreek water showed significant effects on sunscreen cream, with increased absorbance indicating improved UV protection. FTIR analysis revealed that prolonged soaking increases the colloidal formation and bioactive compound concentration, enhancing the health benefits of fenugreek water. The pH of fenugreek water remained relatively stable between 8-9 throughout the study, suggesting minimal impact on the overall effectiveness of the interactions. The findings suggest that fenugreek water plays a crucial role in green catalytic properties that have the potential to reduce diabetes levels and its promising role in enhancing the efficacy of sunscreen creams for skincare treatment, demonstrating the most effective properties for both applications. Also, the study evaluates the UV-blocking and antioxidant properties of fenugreek water, demonstrating its potential as a natural sunscreen additive and free radical scavenger. The observation shows that fenugreek water enhances UV absorption when combined with cream and exhibits peak antioxidant activity on day 2, making it suitable for skincare and pharmaceutical applications.
胡芦巴水以其天然的光彩和双重魔力,成为健康与美丽的绿色催化剂。从控制糖尿病到使肌肤焕发光彩,探索这种古老疗法演变为现代奇迹背后的科学,该研究对胡芦巴水进行了更详细的探讨。本研究调查了胡芦巴水的结构和光学特性,在3天的时间里,研究其与糖溶液、抗糖尿病药物(Diapride M2 Forte)和防晒霜(阴影SPF50 + 面霜)的相互作用。将胡芦巴种子粉浸泡在水中进行X射线衍射(XRD)分析显示,由于形成了凝胶状黏液,从第1天到第3天峰值强度显著增加。与结晶度更高的糖尿病药物相比,胡芦巴种子粉的峰更宽,这反映出多糖结构的有序性较低。对与糖溶液(125毫克/分升、155毫克/分升和185毫克/分升)混合的胡芦巴水进行光学研究表明,吸光度随糖浓度增加而降低,但随胡芦巴水体积增加而增加,这揭示了胶体相互作用。在第1天,吸光度峰值在250纳米左右,但在第2天和第3天,在350纳米处出现了额外的峰值,表明胶体颗粒尺寸在不断变化。当与抗糖尿病药物混合时,胡芦巴水在第3天吸光度增加,表明相互作用增强。此外,胡芦巴水对防晒霜有显著影响,吸光度增加表明紫外线防护能力提高。傅里叶变换红外光谱(FTIR)分析表明,长时间浸泡会增加胶体形成和生物活性化合物浓度,增强胡芦巴水的健康益处。在整个研究过程中,胡芦巴水的pH值在8 - 9之间保持相对稳定,这表明对相互作用的整体效果影响最小。研究结果表明,胡芦巴水在绿色催化特性方面发挥着关键作用,有可能降低糖尿病水平,并且在增强防晒霜用于皮肤护理治疗的功效方面具有潜在作用,证明了其在这两种应用中最有效的特性。此外,该研究评估了胡芦巴水的紫外线阻隔和抗氧化特性,证明了其作为天然防晒添加剂和自由基清除剂的潜力。观察结果表明,胡芦巴水与面霜混合时可增强紫外线吸收,并在第2天表现出峰值抗氧化活性,使其适用于皮肤护理和制药应用。